Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular
diseases and metabolic disorders. Epigenetics is a mechanism to control enzyme …

Significant reprogramming of epigenome is widely described during pathogenesis of breast
cancer. Transformation of normal cell to hyperplastic cell and to neoplastic phenotype is …

During ovarian follicular development, granulosa cells proliferate and progressively
differentiate to support oocyte maturation and ovulation. To determine the underlying links …

Leydig cells of the testis have the capacity to synthesize androgen (mainly testosterone)
from cholesterol. Adult Leydig cells are the cell type for the synthesis of testosterone, which …

The mechanism by which endometriosis, a common gynecological disease characterized by
chronic pelvic pain and infertility, causes infertility remains elusive. Luteinized unruptured …

Objective To investigate whether epigenetic profiles of mural granulosa cells (MGC) and
leukocytes from women with diminished ovarian reserve (DOR) differ from those of women …

Human endometrial stromal cells (ESCs) differentiate into decidual cells by the action of
progesterone, which is essential for implantation and maintenance of pregnancy. We …

The new technology of high‐throughput single‐cell RNA sequencing (10× scRNA‐seq) was
developed recently with many advantages. However, it was not commonly used in farm …

We previously reported that H3K27 acetylation (H3K27ac) increases throughout the genome
during decidualization of human endometrial stromal cells (ESCs). However, its …

We have previously shown that decidualization of human endometrial stromal cells (ESCs)
causes a genome-wide increase in the levels of acetylation of histone-H3 Lys-27 …