The genetics of epilepsy

P Perucca, M Bahlo, SF Berkovic - Annual review of genomics …, 2020 - annualreviews.org
Epilepsy encompasses a group of heterogeneous brain diseases that affect more than 50
million people worldwide. Epilepsy may have discernible structural, infectious, metabolic …

The burden of epilepsy and unmet need in people with focal seizures

P Ioannou, DL Foster, JW Sander, S Dupont… - Brain and …, 2022 - Wiley Online Library
Background Epilepsy is one of the most common neurological conditions worldwide. As a
chronic condition, epilepsy imposes a significant burden on people with epilepsy and …

[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Epilepsy in time of COVID‐19: a survey‐based study

E Fonseca, M Quintana, S Lallana… - Acta Neurologica …, 2020 - Wiley Online Library
Objectives Collateral damage may occur in epilepsy management during the coronavirus
(COVID‐19) pandemic. We aimed to establish the impact of this pandemic on epilepsy …

[HTML][HTML] The impact of epilepsy on quality of life: Findings from a European survey

A Strzelczyk, A Aledo-Serrano, A Coppola, A Didelot… - Epilepsy & Behavior, 2023 - Elsevier
Introduction Epilepsy is a serious neurological disorder affecting the quality of life (QoL) of
people with this condition. A survey was conducted in five European countries (France …

Molecular mechanisms of sex differences in epilepsy and seizure susceptibility in chemical, genetic and acquired epileptogenesis

DS Reddy, W Thompson, G Calderara - Neuroscience letters, 2021 - Elsevier
This article provides a succinct overview of sex differences in epilepsy and putative
molecular mechanisms underlying sex differences in seizure susceptibility in chemical …

Gender and socioeconomic disparities in global burden of epilepsy: an analysis of time trends from 1990 to 2017

Y Hu, Y Shan, Q Du, Y Ding, C Shen, S Wang… - Frontiers in …, 2021 - frontiersin.org
Objective: The objective of the study is to investigate the gender and socioeconomic
disparities in the global burden of epilepsy by prevalence and disability-adjusted life-years …

A comprehensive review on anti-inflammatory response of flavonoids in experimentally-induced epileptic seizures

SS Rabidas, C Prakash, J Tyagi, J Suryavanshi… - Brain Sciences, 2023 - mdpi.com
Flavonoids, a group of natural compounds with phenolic structure, are becoming popular as
alternative medicines obtained from plants. These compounds are reported to have various …

Community-level prevalence of epilepsy and of neurocysticercosis among people with epilepsy in the Balaka district of Malawi: A cross-sectional study

L Keller, D Stelzle, V Schmidt, H Carabin… - PLoS Neglected …, 2022 - journals.plos.org
Background Epilepsy and neurocysticercosis (NCC) prevalence estimates in sub-Saharan
Africa are still scarce but show important variation due to the population studied and different …

[HTML][HTML] Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats

Z Rehman, T Farooq, S Javaid, W Ashraf… - Saudi Pharmaceutical …, 2022 - Elsevier
Introduction The pentylenetetrazol (PTZ)-induced kindling model acts through the
antagonism of central GABA A receptors and is one of the most widely used experimental …