[HTML][HTML] CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in …
L Gan, D Liu, J Liu, E Chen, C Chen, L Liu… - … and Targeted Therapy, 2021 - nature.com
CD38 is the main enzyme for nicotinamide adenine dinucleotide (NAD) degradation in
mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and …
mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and …
Sudan Black B, the specific histochemical stain for lipofuscin: a novel method to detect senescent cells
K Evangelou, VG Gorgoulis - Oncogene-induced senescence: Methods …, 2017 - Springer
Abstract The Sudan-Black-B (SBB) histochemical stain is well known to specifically react
against lipofuscin, an aggregate of oxidized proteins, lipids, and metals. Lipofuscin is related …
against lipofuscin, an aggregate of oxidized proteins, lipids, and metals. Lipofuscin is related …
Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review
HQ Nguyen, NH To, P Zadigue, S Kerbrat… - Critical reviews in …, 2018 - Elsevier
Ionizing radiation-exposure induces a variety of cellular reactions, such as senescence and
apoptosis. Senescence is a permanent arrest state of the cell division, which can be …
apoptosis. Senescence is a permanent arrest state of the cell division, which can be …
Aging diagnostic probe for research on aging and evaluation of anti-aging drug efficacy
Z Li, J Cheng, L Huang, W Li, Y Zhao… - Analytical Chemistry, 2021 - ACS Publications
Aging is a biological process, and its gradual degeneration of physiological functions leads
to an increase in morbidity and mortality. At present, more and more studies on aging and …
to an increase in morbidity and mortality. At present, more and more studies on aging and …
[HTML][HTML] ROS-induced activation of DNA damage responses drives senescence-like state in postmitotic cochlear cells: implication for hearing preservation
N Benkafadar, F François, C Affortit, F Casas… - Molecular …, 2019 - Springer
In our aging society, age-related hearing loss (ARHL) has become a major socioeconomic
issue. Reactive oxygen species (ROS) may be one of the main causal factors of age-related …
issue. Reactive oxygen species (ROS) may be one of the main causal factors of age-related …
[HTML][HTML] Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders
In brief Placental oxidative stress contributes to both normal and abnormal placentation
during pregnancy. This review discusses the potential consequence of oxidative stress …
during pregnancy. This review discusses the potential consequence of oxidative stress …
Chemical Strategies for the Detection and Elimination of Senescent Cells
J García-Fleitas, A García-Fernández… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Cellular senescence can be defined as an irreversible stopping of cell
proliferation that arises in response to various stress signals. Cellular senescence is …
proliferation that arises in response to various stress signals. Cellular senescence is …
[HTML][HTML] Integrating environment and aging research: opportunities for synergy and acceleration
Despite significant overlaps in mission, the fields of environmental health sciences and
aging biology are just beginning to intersect. It is increasingly clear that genetics alone does …
aging biology are just beginning to intersect. It is increasingly clear that genetics alone does …
Ageing, cellular senescence and chronic kidney disease: experimental evidence
H Tan, J Xu, Y Liu - Current opinion in nephrology and …, 2022 - journals.lww.com
Ageing, cellular senescence and chronic kidney disease: expe... : Current Opinion in Nephrology
and Hypertension Ageing, cellular senescence and chronic kidney disease: experimental …
and Hypertension Ageing, cellular senescence and chronic kidney disease: experimental …
Inducers of senescence, toxic compounds, and senolytics: The multiple faces of Nrf2‐activating phytochemicals in cancer adjuvant therapy
M Malavolta, M Bracci, L Santarelli… - Mediators of …, 2018 - Wiley Online Library
The reactivation of senescence in cancer and the subsequent clearance of senescent cells
are suggested as therapeutic intervention in the eradication of cancer. Several natural …
are suggested as therapeutic intervention in the eradication of cancer. Several natural …