Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
The characteristics and the multiple functions of integrin β1 in human cancers
L Sun, S Guo, Y Xie, Y Yao - Journal of Translational Medicine, 2023 - Springer
Integrins, which consist of two non-covalently linked α and β subunits, play a crucial role in
cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 …
cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 …
[HTML][HTML] Bioinspired core-shell nanofiber drug-delivery system modulates osteogenic and osteoclast activity for bone tissue regeneration
S Anjum, Y Wang, Y Xin, X Li, T Li, H Zhang, L Quan… - Materials Today Bio, 2024 - Elsevier
Osteogenic-osteoclast coupling processes play a crucial role in bone regeneration.
Recently, strategies that focus on multi-functionalized implant surfaces to enhance the …
Recently, strategies that focus on multi-functionalized implant surfaces to enhance the …
Therapeutic resistance models and treatment sequencing in advanced prostate cancer
Simple Summary Castration-resistant prostate cancer (CRPC) treatments include next-
generation anti-androgen therapies (NGATs), taxane therapy, and PARP inhibitors (PARPi) …
generation anti-androgen therapies (NGATs), taxane therapy, and PARP inhibitors (PARPi) …
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer
A Geethadevi, Z Ku, SW Tsaih, D Parashar… - NPJ Precision …, 2024 - nature.com
Chemotherapy such as cisplatin is widely used to treat ovarian cancer either before or after
surgical debulking. However, cancer relapse due to chemotherapy resistance is a major …
surgical debulking. However, cancer relapse due to chemotherapy resistance is a major …
Gamma radiation assisted green synthesis of hesperidin-reduced graphene oxide nanocomposite targeted JNK/SMAD4/MMP2 signaling pathway
AS Kodous, EO Taha, DF El-Maghraby, AA Hassana… - Scientific Reports, 2024 - nature.com
In this study, a novel method for the fabrication of hesperidin/reduced graphene oxide
nanocomposite (RGOH) with the assistance of gamma rays is reported. The different RGOHs …
nanocomposite (RGOH) with the assistance of gamma rays is reported. The different RGOHs …
Identifying alkaline phosphatase inhibitory potential of cyclooxygenase-2 inhibitors: Insights from molecular docking, MD simulations, molecular expression analysis in …
Abstract Alkaline phosphatases (APs, EC 3.1. 3.1) belong to a superfamily of biological
macromolecules that dephosphorylate many phosphometabolites and phosphoproteins and …
macromolecules that dephosphorylate many phosphometabolites and phosphoproteins and …
Assessment of the proteome profile of decellularized human amniotic membrane and its biocompatibility with umbilical cord‐derived mesenchymal stem cells
K Ahmed, H Tauseef, JA Ainuddin… - … Research Part A, 2024 - Wiley Online Library
Extracellular matrix‐based bio‐scaffolds are useful for tissue engineering as they retain the
unique structural, mechanical, and physiological microenvironment of the tissue thus …
unique structural, mechanical, and physiological microenvironment of the tissue thus …
FNDC5 inhibits malignant growth of human cervical cancer cells via restraining PI3K/AKT pathway
N Li, XL Wang, R Ge, Y Wang, XL Tian… - Journal of Cellular …, 2024 - Wiley Online Library
Cervical cancer (CxCa) is the fourth most frequent cancer in women. This study aimed to
determine the role and underlying mechanism of fibronectin type III domain‐containing …
determine the role and underlying mechanism of fibronectin type III domain‐containing …
Shaping Oncogenic Microenvironments: Contribution of Fibronectin
G Guerrero-Barberà, N Burday… - Frontiers in Cell and …, 2024 - frontiersin.org
The extracellular matrix (ECM) is a complex network of proteins and glycans, dynamically
remodeled and specifically tailored to the structure/function of each organ. The malignant …
remodeled and specifically tailored to the structure/function of each organ. The malignant …