The intrinsic autofluorescence of biological tissues interferes with the detection of
fluorophores administered for fluorescence guidance, an emerging auxiliary technique in …

Advanced stage glioma is the most aggressive form of malignant brain tumors with a short
survival time. Real-time pathology assisted, or image guided surgical procedures that …

The review begins with an overview of the fundamental principles/physics underlying light,
fluorescence, and other light-matter interactions in biological tissues. It then focuses on 5 …

Gliomas are diffuse and hard to cure brain tumors. A major reason for their aggressive
behavior is their property to infiltrate the brain. The gross appearance of the infiltrative …

UNESCO (the United Nations Educational, Scientific, and Cultural Organization) has
declared 2015 the “International Year of Light and Light-Based Technologies”. In celebration …

A key challenge of central nervous system tumor surgery is to discriminate between brain
regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of …

Delineating tumor margins as accurately as possible is of primordial importance in surgical
oncology: extent of resection is associated with survival but respect of healthy surrounding …

Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …

The primary line of therapy for high-grade brain tumor is surgical resection, however,
identifying tumor margins in vivo remains a major challenge. Despite the progress in …

The study utilizes autofluorescence spectroscopy (AFS) along with multivariate spectral
analysis for differentiating various stages of hepatic fibrosis. AFS has recently emerged as …