The crucial role and mechanism of insulin resistance in metabolic disease

X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Biomechanics and mechanobiology of the bone matrix

C Ma, T Du, X Niu, Y Fan - Bone research, 2022 - nature.com
The bone matrix plays an indispensable role in the human body, and its unique
biomechanical and mechanobiological properties have received much attention. The bone …

Osteometabolism: metabolic alterations in bone pathologies

RK Srivastava, L Sapra, PK Mishra - Cells, 2022 - mdpi.com
Renewing interest in the study of intermediate metabolism and cellular bioenergetics is
brought on by the global increase in the prevalence of metabolic illnesses. Understanding of …

A brief review of bone cell function and importance

V Šromová, D Sobola, P Kaspar - Cells, 2023 - mdpi.com
This review focuses on understanding the macroscopic and microscopic characteristics of
bone tissue and reviews current knowledge of its physiology. It explores how these features …

The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice

L Jin, S Han, X Lv, X Li, Z Zhang, H Kuang… - Nature …, 2023 - nature.com
Skeletal muscle and thermogenic adipose tissue are both critical for the maintenance of
body temperature in mammals. However, whether these two tissues are interconnected to …

Reduced bone formation and increased bone resorption drive bone loss in Eimeria infected broilers

YH Tompkins, J Choi, PY Teng, M Yamada… - Scientific Reports, 2023 - nature.com
Coccidiosis is an economically significant disease in the global poultry industry, but little is
known about the mechanisms of bone defects caused by coccidiosis; thus, the study focused …

运动与肠道菌健康效益的关系

梁家琪, 刘恒旭, 阳金鑫, 杨椅, 邓旭辉, 谭明健, 罗炯 - 中国组织工程研究, 2023 - cjter.com
运动与肠道菌健康效益的关系 中国组织工程研究 首页 关于本刊 编委会 在线投稿 期刊公告
出版道德 OA政策 作者学院 在线问答 联系我们 English 中国组织工程研究 ›› 2023, Vol. 27 ›› …

Epigenetic regulation of bone remodeling and bone metastasis

G Sharma, A Sultana, KM Abdullah, R Pothuraju… - Seminars in Cell & …, 2024 - Elsevier
Bone remodeling is a continuous and dynamic process of bone formation and resorption to
maintain its integrity and homeostasis. Bone marrow is a source of various cell lineages …

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

N Spielmann, G Miller, TI Oprea, CW Hsu… - Nature Cardiovascular …, 2022 - nature.com
Clinical presentation of congenital heart disease is heterogeneous, making identification of
the disease-causing genes and their genetic pathways and mechanisms of action …

Sympathetic innervation regulates osteocyte‐mediated cortical bone resorption during lactation

Q Guo, N Chen, C Qian, C Qi, K Noller… - Advanced …, 2023 - Wiley Online Library
Bone undergoes constant remodeling by osteoclast bone resorption coupled with osteoblast
bone formation at the bone surface. A third major cell type in the bone is osteocytes, which …