Neutrophilic dermatoses are a group of conditions characterized by the accumulation of
neutrophils in the skin and clinically presenting with polymorphic cutaneous lesions …

Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

Abstract Purpose of Review Extraintestinal manifestations (EIMs) of inflammatory bowel
disease (IBD) represent a complex array of disease processes with variable epidemiologic …

Inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory disease of the
gastrointestinal tract. In addition to digestive symptoms, patients with IBD may also develop …

Adult-onset Still's disease (AOSD) is a non-familial, polygenic systemic autoinflammatory
disorder. It is traditionally characterized by four cardinal manifestations—spiking fever, an …

(1) Background: Colchicine is a natural alkaloid with anti-inflammatory properties used to
treat various disorders, including some skin diseases. This paper aims to incorporate all the …

Skin manifestations of systemic disease and malignancy are extremely polymorphous.
Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an …

Pyoderma Gangrenosum (PG) is a rare neutrophilic dermatosis with multiple different
clinical presentations and associated comorbidities. PG has historically been a challenging …

Systemic amyloidosis can be hereditary or acquired with autosomal dominant mutations in
the transthyretin gene (TTR) being the most common cause of hereditary amyloidosis …

Pyoderma gangrenosum (PG) is a rare autoinflammatory ulcerative neutrophilic skin
disease. Its clinical presentation is a rapidly progressing painful skin ulcer with ill-defined …