[HTML][HTML] Why are viscosity and nonlinearity bound to make an impact in clinical elastographic diagnosis?

G Rus, IH Faris, J Torres, A Callejas, J Melchor - Sensors, 2020 - mdpi.com
The adoption of multiscale approaches by the biomechanical community has caused a
major improvement in quality in the mechanical characterization of soft tissues. The recent …

[HTML][HTML] Multimodal experimental studies of the passive mechanical behavior of human aortas: current approaches and future directions

A Pukaluk, G Sommer, GA Holzapfel - Acta Biomaterialia, 2024 - Elsevier
Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …

Mechanics of cervical remodelling: insights from rodent models of pregnancy

K Yoshida, C Jayyosi, N Lee… - Interface …, 2019 - royalsocietypublishing.org
The uterine cervix undergoes a complex remodelling process during pregnancy,
characterized by dramatic changes in both extracellular matrix (ECM) structure and …

Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers

S Nallasamy, K Yoshida, M Akins, K Myers… - …, 2017 - academic.oup.com
The extracellular matrix (ECM) plays an active and dynamic role that both reflects and
facilitates the functional requirements of a tissue. The mature ECM of the nonpregnant cervix …

[HTML][HTML] Changes in the microstructure of the human aortic adventitia under biaxial loading investigated by multi-photon microscopy

A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2023 - Elsevier
Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …

Differences in collagen fiber diameter and waviness between healthy and aneurysmal abdominal aortas

JA Niestrawska, A Pukaluk, AR Babu… - Microscopy and …, 2022 - academic.oup.com
Collagen plays a key role in the strength of aortic walls, so studying micro-structural changes
during disease development is critical to better understand collagen reorganization. Second …

[HTML][HTML] Multiscale computational modeling of arterial micromechanics: A review

M Dalbosco, EA Fancello, GA Holzapfel - Computer Methods in Applied …, 2024 - Elsevier
The mechanical properties of arterial tissue play a central role in healthy human physiology
and have therefore been extensively studied and modeled in recent decades. These …

[HTML][HTML] Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection

O Gültekin, SP Hager, H Dal, GA Holzapfel - Biomechanics and modeling …, 2019 - Springer
This study analyzes the lethal clinical condition of aortic dissections from a numerical point
of view. On the basis of previous contributions by Gültekin et al.(Comput Methods Appl Mech …

Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy

M Colon-Caraballo, N Lee, S Nallasamy, K Myers… - Matrix Biology, 2022 - Elsevier
A bstract The cervix undergoes rapid and dramatic shifts in collagen and elastic fiber
structure to achieve its disparate physiological roles of competence during pregnancy and …

Effect of Ultraviolet Radiation on the Enzymolytic and Biomechanical Profiles of Abdominal Aortic Adventitia Tissue

EM Arbănaşi, E Russu, EM Arbănaşi… - Journal of Clinical …, 2024 - mdpi.com
Background: The abdominal aortic aneurysm (AAA) is defined as an increase in aortic
diameter by more than 50% and is associated with a high risk of rupture and mortality …