A new pathway for mitochondrial quality control: mitochondrial‐derived vesicles

A Sugiura, GL McLelland, EA Fon, HM McBride - The EMBO journal, 2014 - embopress.org
The last decade has been marked by tremendous progress in our understanding of the cell
biology of mitochondria, with the identification of molecules and mechanisms that regulate …

Peroxisomes take shape

JJ Smith, JD Aitchison - Nature reviews Molecular cell biology, 2013 - nature.com
Peroxisomes carry out various oxidative reactions that are tightly regulated to adapt to the
changing needs of the cell and varying external environments. Accordingly, they are …

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

A Sugiura, S Mattie, J Prudent, HM McBride - Nature, 2017 - nature.com
Peroxisomes function together with mitochondria in a number of essential biochemical
pathways, from bile acid synthesis to fatty acid oxidation. Peroxisomes grow and divide from …

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

R Hua, D Cheng, É Coyaud, S Freeman… - Journal of Cell …, 2017 - rupress.org
Lipid exchange between the endoplasmic reticulum (ER) and peroxisomes is necessary for
the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome …

Endoplasmic reticulum structure and interconnections with other organelles

AR English, GK Voeltz - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) is a large, continuous membrane-bound organelle
comprised of functionally and structurally distinct domains including the nuclear envelope …

Peroxisomes as cellular adaptors to metabolic and environmental stress

A He, JM Dean, IJ Lodhi - Trends in cell biology, 2021 - cell.com
Peroxisomes are involved in multiple metabolic processes, including fatty acid oxidation,
ether lipid synthesis, and reactive oxygen species (ROS) metabolism. Recent studies …

Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

S Wang, FZ Idrissi, M Hermansson, A Grippa… - Nature …, 2018 - nature.com
Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …

Rab10 GTPase regulates ER dynamics and morphology

AR English, GK Voeltz - Nature cell biology, 2013 - nature.com
We have identified Rab10 as an ER-specific Rab GTPase that regulates ER structure and
dynamics. We show that Rab10 localizes to the ER and to dynamic ER-associated structures …

The different facets of organelle interplay—an overview of organelle interactions

M Schrader, LF Godinho, JL Costello… - Frontiers in cell and …, 2015 - frontiersin.org
Membrane-bound organelles such as mitochondria, peroxisomes, or the endoplasmic
reticulum (ER) create distinct environments to promote specific cellular tasks such as ATP …

[HTML][HTML] No peroxisome is an island—peroxisome contact sites

N Shai, M Schuldiner, E Zalckvar - … et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
In order to optimize their multiple cellular functions, peroxisomes must collaborate and
communicate with the surrounding organelles. A common way of communication between …