Tumor microenvironment and nanotherapeutics: intruding the tumor fort

AVVVR Kiran, GK Kumari, PT Krishnamurthy… - Biomaterials …, 2021 - pubs.rsc.org
Over recent years, advancements in nanomedicine have allowed new approaches to
diagnose and treat tumors. Nano drug delivery systems exploit the enhanced permeability …

Cancer immunotherapy

RO Dillman - Cancer biotherapy & radiopharmaceuticals, 2011 - liebertpub.com
Summation Cancer immunotherapy consists of approaches that modify the host immune
system, and/or the utilization of components of the immune system, as cancer treatment …

Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance

BM Olson, JA Sullivan, WJ Burlingham - Frontiers in Immunology, 2013 - frontiersin.org
The importance of regulatory T cells (Tregs) in balancing the effector arm of the immune
system is well documented, playing a central role in preventing autoimmunity, facilitating …

Camouflage and sabotage: tumor escape from the immune system

I Poschke, D Mougiakakos, R Kiessling - Cancer Immunology …, 2011 - Springer
The field of tumor immunology has made great progress in understanding tumor immune
interactions. As a consequence a number of immuno-therapeutic approaches have been …

Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer

JG Aerts, JP Hegmans - Cancer research, 2013 - AACR
There is growing evidence that activation of the immune system may be an effective
treatment for patients with either small cell lung cancer or non–small cell lung cancer …

The immunomodulatory effects of mesenchymal stem cell polarization within the tumor microenvironment niche

CM Rivera-Cruz, JJ Shearer… - Stem cells …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy, particularly for
their antitumor effects. This cell population can be isolated from multiple tissue sources and …

HGF/MET and the immune system: relevance for cancer immunotherapy

F Papaccio, CM Della Corte, G Viscardi… - International journal of …, 2018 - mdpi.com
An overactivation of hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor
(MET) axis promotes tumorigenesis and tumor progression in various cancer types …

Immunosuppressive networks and checkpoints controlling antitumor immunity and their blockade in the development of cancer immunotherapeutics and vaccines

AQ Butt, KHG Mills - Oncogene, 2014 - nature.com
Vaccines that promote protective adaptive immune responses have been successfully
developed against a range of infectious diseases, and these are normally administered prior …

Gene polymorphisms and biological effects of vitamin D receptor on nonalcoholic fatty liver disease development and progression

E Tourkochristou, A Mouzaki, C Triantos - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with
increasing prevalence worldwide. The genetic and molecular background of NAFLD …

Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder

E Xylinas, BD Robinson, LA Kluth, BG Volkmer… - European Journal of …, 2014 - Elsevier
Purpose Expression of T-cell co-regulatory proteins has been associated with worse
outcomes in patients with UCB. We aimed to confirm these findings. Materials and methods …