Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery

A Ayati, S Emami, A Asadipour, A Shafiee… - European Journal of …, 2015 - Elsevier
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …

[HTML][HTML] Cytotoxicity of dietary flavonoids on different human cancer types

K Sak - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Flavonoids are ubiquitous in nature. They are also in food, providing an essential link
between diet and prevention of chronic diseases including cancer. Anticancer effects of …

Flavonoids targeting HIF-1: Implications on cancer metabolism

M Samec, A Liskova, L Koklesova, S Mersakova… - Cancers, 2021 - mdpi.com
Simple Summary This comprehensive review discusses the anticancer effects of plant
phenolic compounds, known as flavonoids, through the targeting of HIF-1 and critical …

The current state of knowledge in biological properties of cirsimaritin

T Benali, I Jaouadi, R Ghchime, N El Omari, K Harboul… - Antioxidants, 2022 - mdpi.com
The search for natural plant-based products as new pharmacological alternatives to treat
various human pathologies has taken on great importance for researchers and research …

Pharmaceutical important phenolic compounds overproduction and gene expression analysis in Dracocephalum kotschyi hairy roots elicited by SiO2 nanoparticles

E Nourozi, B Hosseini, R Maleki… - Industrial Crops and …, 2019 - Elsevier
Dracocephalum kotschyi Boiss. is one of the important threatened traditional species of
medicinal herbs; last pharmaceutical research has shown that rosmarinic acid (RA) and …

[HTML][HTML] Effects of apigenin on gastric cancer cells

A Pratas, B Malhão, R Palma, P Mendonça… - Biomedicine & …, 2024 - Elsevier
Gastric Cancer (GC) is one of the most prevalent cancers worldwide. As the currently
available therapeutic options are invasive, new and more benign options are being …

Medicinal Properties and Active Constituents of Dracocephalum kotschyi and Its Significance in Iran: A Systematic Review

P Heydari, M Yavari, P Adibi, G Asghari… - Evidence‐Based …, 2019 - Wiley Online Library
Objectives. Dracocephalum has over 60 species and is found mainly in the temperate
regions of Asia and Europe. One of these species, ie, Dracocephalum kotschyi Boiss, is …

Methoxylated flavones: occurrence, importance, biosynthesis

A Berim, DR Gang - Phytochemistry reviews, 2016 - Springer
Lipophilic flavones with several methoxyl residues occur in various clades of land plants,
from liverworts to core eudicots. Their chemodiversity is mediated by the manifold …

Correlation of antiangiogenic, antioxidant and cytotoxic activities of some Sudanese medicinal plants with phenolic and flavonoid contents

LEA Hassan, MBK Ahamed, ASA Majid… - … and alternative medicine, 2014 - Springer
Background Consumption of medicinal plants to overcome diseases is traditionally belongs
to the characteristics of most cultures on this earth. Sudan has been a host and cradle to …

Chitosan stimulates secondary metabolite production and nutrient uptake in medicinal plant Dracocephalum kotschyi

S Kahromi, J Khara - Journal of the Science of Food and …, 2021 - Wiley Online Library
BACKGROUND A wide variety of secondary metabolites are synthesized from primary
metabolites by plants which have a vast range in pharmaceutical, food additive and …