Since the beginning of the COVID-19 pandemic, reduced incidence of many viral and
bacterial infections has been reported in children: bronchiolitis, varicella, measles, pertussis …

Pertussis (whooping cough) is a respiratory disease caused primarily by Bordetella
pertussis, a Gram-negative bacteria. Pertussis is a relatively contagious infectious disease in …

Background Bordetella pertussis is the main agent of whooping cough. Vaccination with
acellular pertussis vaccines has been largely implemented in high-income countries. These …

Pertussis, also known as whooping cough, is a resurging acute respiratory disease of
humans primarily caused by the Gram-negative coccobacilli Bordetella pertussis, and less …

Background The national immunization program in Mexico includes a 3-dose primary series
of pertussis vaccine and a toddler booster dose. In Mexico, whole-cell pertussis vaccines …

Traditional vaccine development against infectious diseases has been guided by the
overarching aim to generate efficacious vaccines normally indicated by an antibody and/or …

Bordetella pertussis whole-cell vaccines (wP) caused a spectacular drop of global pertussis
incidence, but since the replacement of wP with acellular pertussis vaccines (aP), pertussis …

Pertussis (whooping cough) epidemics persist globally despite high vaccine coverage
among infants and young children. The resurgence of pertussis in high-income countries is …

Introduction Whole cell and acellular pertussis vaccines have been very effective in
decreasing the deaths of neonates and infants from Bordetella pertussis. Despite high …

The increased incidence of whooping cough worldwide suggests that current vaccination
against Bordetella pertussis infection has limitations in quality and duration of protection …