[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management
AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …
[HTML][HTML] Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms
S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
[HTML][HTML] Tetraspanins, more than markers of extracellular vesicles in reproduction
J Jankovičová, P Sečová, K Michalková… - International Journal of …, 2020 - mdpi.com
The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
Y Lee, S El Andaloussi, MJA Wood - Human molecular genetics, 2012 - academic.oup.com
Exosomes and microvesicles are extracellular nanovesicles released by most but not all
cells. They are specifically equipped to mediate intercellular communication via the transfer …
cells. They are specifically equipped to mediate intercellular communication via the transfer …
[HTML][HTML] Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles
Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo: Part I: Health and Normal Physiology
Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …
now known to mediate physiological and pathological functions throughout the body. We …
[HTML][HTML] Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells
A Waldenström, N Gennebäck, U Hellman, G Ronquist - PloS one, 2012 - journals.plos.org
Background Shedding microvesicles are membrane released vesicles derived directly from
the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin …
the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin …
Preparation and characterization of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by every cell
type and offer significant potential in therapy and diagnostics. Differential ultracentrifugation …
type and offer significant potential in therapy and diagnostics. Differential ultracentrifugation …