[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management

AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

[HTML][HTML] Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms

S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …

[HTML][HTML] Tetraspanins, more than markers of extracellular vesicles in reproduction

J Jankovičová, P Sečová, K Michalková… - International Journal of …, 2020 - mdpi.com
The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

KW Witwer, EI Buzás, LT Bemis, A Bora… - Journal of …, 2013 - Taylor & Francis
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …

Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

Y Lee, S El Andaloussi, MJA Wood - Human molecular genetics, 2012 - academic.oup.com
Exosomes and microvesicles are extracellular nanovesicles released by most but not all
cells. They are specifically equipped to mediate intercellular communication via the transfer …

[HTML][HTML] Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles

N Iraci, T Leonardi, F Gessler, B Vega… - International journal of …, 2016 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …

In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo: Part I: Health and Normal Physiology

AG Yates, RC Pink, U Erdbrügger… - Journal of …, 2022 - Wiley Online Library
Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …

[HTML][HTML] Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells

A Waldenström, N Gennebäck, U Hellman, G Ronquist - PloS one, 2012 - journals.plos.org
Background Shedding microvesicles are membrane released vesicles derived directly from
the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin …

Preparation and characterization of extracellular vesicles

S Tiwari, V Kumar, S Randhawa… - American Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by every cell
type and offer significant potential in therapy and diagnostics. Differential ultracentrifugation …