Microparticles, microspheres, and microcapsules are widely used constituents of
multiparticulate drug delivery systems, offering both therapeutic and technological …

This literature review is a compilation of the composition and, in most cases, the preparation
instructions for simulated biological fluids that may be used as dissolution media in the …

The use of simulated biological fluids (SBFs) is a promising in vitro technique to better
understand the release mechanisms and possible in vivo behaviour of materials, including …

Nanoparticles bring many benefits to pulmonary drug delivery applications, especially for
systemic delivery and drugs with poor solubility. They have recently been explored in …

Delivering therapeutic agents to the lungs requires a deep understanding of the kinetics and
dynamics of drugs in this biologically and physiologically complex system. In this chapter …

An investigation for assessing pulmonary bioaccessibility of metals from reference materials
is presented using simulated lung fluids. The objective of this paper was to contribute to an …

Abstract The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral
immediate release drugs, is utilized by R&D scientists and regulators to streamline product …

Asthma is a worldwide health problem. Activated T cells (ATCs) in the lung, particularly T
helper 2 cells (Th 2), are strongly associated with inducing airway inflammatory responses …

Prediction of local exposure following inhalation of a locally acting pulmonary drug is central
to the successful development of novel inhaled medicines, as well as generic equivalents …

Inhalation therapy treating severe infectious disease is among the more complex and
emerging topics in controlled drug release. Micron-sized carriers are needed to deposit …