COVID-19: Transmission, prevention, and potential therapeutic opportunities

M Lotfi, MR Hamblin, N Rezaei - Clinica chimica acta, 2020 - Elsevier
The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense …

[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

Shedding of SARS-CoV-2 in feces and urine and its potential role in person-to-person transmission and the environment-based spread of COVID-19

DL Jones, MQ Baluja, DW Graham, A Corbishley… - Science of the Total …, 2020 - Elsevier
The recent detection of SARS-CoV-2 RNA in feces has led to speculation that it can be
transmitted via the fecal-oral/ocular route. This review aims to critically evaluate the …

[HTML][HTML] Saliva: potential diagnostic value and transmission of 2019-nCoV

R Xu, B Cui, X Duan, P Zhang, X Zhou… - International journal of …, 2020 - nature.com
nCoV epidemic was firstly reported at late December of 2019 and has caused a global
outbreak of COVID-19 now. Saliva, a biofluid largely generated from salivary glands in oral …

A Guide to COVID‐19: a global pandemic caused by the novel coronavirus SARS‐CoV‐2

CL Atzrodt, I Maknojia, RDP McCarthy… - The FEBS …, 2020 - Wiley Online Library
The emergence of the SARS‐CoV‐2 strain of the human coronavirus has thrown the world
into the midst of a new pandemic. In the human body, the virus causes COVID‐19, a disease …

[HTML][HTML] Overview of lethal human coronaviruses

B Chen, EK Tian, B He, L Tian, R Han… - Signal transduction and …, 2020 - nature.com
Coronavirus infections of multiple origins have spread to date worldwide, causing severe
respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV …

[HTML][HTML] Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants

R Wang, J Chen, K Gao, Y Hozumi, C Yin… - Communications …, 2021 - nature.com
SARS-CoV-2 has been mutating since it was first sequenced in early January 2020. Here,
we analyze 45,494 complete SARS-CoV-2 geneome sequences in the world to understand …

Key interacting residues between RBD of SARS-CoV-2 and ACE2 receptor: combination of molecular dynamics simulation and density functional calculation

B Jawad, P Adhikari, R Podgornik… - Journal of chemical …, 2021 - ACS Publications
The spike protein of SARS-CoV-2 binds to the ACE2 receptor via its receptor-binding
domain (RBD), with the RBD–ACE2 complex presenting an essential molecular target for …

[HTML][HTML] COVID-19 and the kidney: from epidemiology to clinical practice

I Gagliardi, G Patella, A Michael, R Serra… - Journal of clinical …, 2020 - mdpi.com
The new respiratory infectious disease coronavirus disease 2019 (COVID-19) that
originated in Wuhan, China, in December 2019 and caused by a new strain of zoonotic …

Is the rigidity of SARS-CoV-2 spike receptor-binding motif the hallmark for its enhanced infectivity? Insights from all-atom simulations

A Spinello, A Saltalamacchia… - The journal of physical …, 2020 - ACS Publications
The severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic is setting the
global health crisis of our time, causing a devastating societal and economic burden. An …