[HTML][HTML] Therapeutic potential of mesenchymal stem cells for cancer therapy

A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

Traumatic brain injury: current treatment strategies and future endeavors

M Galgano, G Toshkezi, X Qiu, T Russell… - Cell …, 2017 - journals.sagepub.com
Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of
consciousness to an unrelenting comatose state and death. In the most severe form of TBI …

Transplantation of human mesenchymal stem-cell-derived exosomes immobilized in an adhesive hydrogel for effective treatment of spinal cord injury

L Li, Y Zhang, J Mu, J Chen, C Zhang, H Cao, J Gao - Nano letters, 2020 - ACS Publications
Spinal cord injury is among the most fatal diseases. The complicated inhibitory
microenvironment requires comprehensive mitigation. Exosomes derived from …

A MnO2 Nanoparticle-Dotted Hydrogel Promotes Spinal Cord Repair via Regulating Reactive Oxygen Species Microenvironment and Synergizing with …

L Li, B Xiao, J Mu, Y Zhang, C Zhang, H Cao, R Chen… - ACS …, 2019 - ACS Publications
Spinal cord injury (SCI) is one of the most debilitating injuries, and transplantation of stem
cells in a scaffold is a promising strategy for treatment. However, stem cell treatment of SCI …

ROS‐Scavenging Hydrogels Synergize with Neural Stem Cells to Enhance Spinal Cord Injury Repair via Regulating Microenvironment and Facilitating Nerve …

D Liu, G Lu, B Shi, H Ni, J Wang, Y Qiu… - Advanced …, 2023 - Wiley Online Library
Although stem cell‐based therapy is recognized as a promising therapeutic strategy for
spinal cord injury (SCI), its efficacy is greatly limited by local reactive oxygen species (ROS) …

Smart biomaterials and their potential applications in tissue engineering

HM Khan, X Liao, BA Sheikh, Y Wang, Z Su… - Journal of Materials …, 2022 - pubs.rsc.org
Smart biomaterials have been rapidly advancing ever since the concept of tissue
engineering was proposed. Interacting with human cells, smart biomaterials can play a key …

Developing a mechanically matched decellularized spinal cord scaffold for the in situ matrix-based neural repair of spinal cord injury

Y Ma, H Shi, Q Wei, Q Deng, J Sun, Z Liu, B Lai, G Li… - Biomaterials, 2021 - Elsevier
Tissue engineering is a promising strategy to repair spinal cord injury (SCI). However, a
bioscaffold with mechanical properties that match those of the pathological spinal cord …

Sustained release SDF-1α/TGF-β1-loaded silk fibroin-porous gelatin scaffold promotes cartilage repair

Y Chen, T Wu, S Huang, CWW Suen… - … applied materials & …, 2019 - ACS Publications
Continuous delivery of growth factors to the injury site is crucial to creating a favorable
microenvironment for cartilage injury repair. In the present study, we fabricated a novel …

Roles of mesenchymal stem cells in spinal cord injury

J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

[HTML][HTML] Biomaterial-supported cell transplantation treatments for spinal cord injury: challenges and perspectives

S Liu, T Schackel, N Weidner… - Frontiers in cellular …, 2018 - frontiersin.org
Spinal cord injury (SCI), resulting in para-and tetraplegia caused by the partial or complete
disruption of descending motor and ascending sensory neurons, represents a complex …