The role of inflammation in the pathogenesis of osteoarthritis
YY Chow, KY Chin - Mediators of inflammation, 2020 - Wiley Online Library
A joint is the point of connection between two bones in our body. Inflammation of the joint
leads to several diseases, including osteoarthritis, which is the concern of this review …
leads to several diseases, including osteoarthritis, which is the concern of this review …
[PDF][PDF] Damage-associated molecular patterns in inflammatory diseases
JS Roh, DH Sohn - Immune network, 2018 - synapse.koreamed.org
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …
are released from damaged or dying cells and activate the innate immune system by …
Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …
most widespread arthritis in the world, using the powerful tool of single-cell RNA …
Chondrocyte dedifferentiation and osteoarthritis (OA)
E Charlier, C Deroyer, F Ciregia, O Malaise… - Biochemical …, 2019 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …
degradation but also synovial membrane inflammation, osteophyte formation and …
The development of disease-modifying therapies for osteoarthritis (DMOADs): the evidence to date
Osteoarthritis (OA) is a complex heterogeneous articular disease with multiple joint tissue
involvement of varying severity and no regulatory-agency-approved disease-modifying …
involvement of varying severity and no regulatory-agency-approved disease-modifying …
Synovitis in osteoarthritis: current understanding with therapeutic implications
A Mathiessen, PG Conaghan - Arthritis research & therapy, 2017 - Springer
Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
[HTML][HTML] Macrophages regulate the progression of osteoarthritis
H Zhang, D Cai, X Bai - Osteoarthritis and cartilage, 2020 - Elsevier
OA is now well accepted as a low-grade inflammatory disease affecting the whole joint. In
addition to mechanical loading, inflammation (particularly synovitis), contributes significantly …
addition to mechanical loading, inflammation (particularly synovitis), contributes significantly …
Cartilage diseases
Y Krishnan, AJ Grodzinsky - Matrix Biology, 2018 - Elsevier
Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human
body including bearing loads in articular joints and intervertebral discs, providing joint …
body including bearing loads in articular joints and intervertebral discs, providing joint …
Dietary inflammatory index and non-communicable disease risk: a narrative review
There are over 1,000,000 publications on diet and health and over 480,000 references on
inflammation in the National Library of Medicine database. In addition, there have now been …
inflammation in the National Library of Medicine database. In addition, there have now been …