Mitoxantrone (Novantrone®), a synthetic anthracenedione derivative, is an antineoplastic,
immunomodulatory agent. Its presumed mechanism of action in patients with multiple …

Glatiramer acetate is a synthetic copolymer composed of a random mixture of four amino
acids that modifies the immune response that results in the CNS inflammation …

This study assessed the feasibility of using a self-report questionnaire to measure
neurological impairment in multiple sclerosis (MS). Thirty patients aged 21-67 years …

The majority of patients with relapse-onset multiple sclerosis (MS) will go on to develop
secondary-progressive MS (SPMS) disease, with approximately 50% developing SPMS …

Cladribine is a deaminase-resistant deoxyadenosine analogue that selectively reduces
lymphocyte counts. The drug is an effective therapy for selected haematological …

The presumed but as yet unspecified autoimmune-mediated basis for the pathogenesis of
multiple sclerosis has led to attempts to modify the immune system of patients with this …

SciELO - Brasil - Recomendações quanto ao uso de drogas imunomoduladoras na esclerose
múltipla: o consenso do BCTRIMS Recomendações quanto ao uso de drogas …

This review focuses on Rebif®, one of 2 available formulations of recombinant interferon-β-
1a, a molecule with the same molecular weight and primary structure as native interferon-β …

In the last quarter-century the assault on motor neurone disease (MND)/amyotrophic lateral
sclerosis (ALS) was initiated by single-center small clinical trials with technically complex …

Multiple sclerosis (MS) is a chronic neurological disease of adults that affects over 1 million
people worldwide. Relapsing-remitting MS, characterized by acute attacks (relapses) …