Innovative Strategies for Photoallergy Assessment: Breaking Free from Animal Models in Cosmetic Ingredient Development
AS Maddaleno, MP Vinardell, M Mitjans - Cosmetics, 2024 - mdpi.com
Photoallergy, a unique form of skin sensitization induced by specific compounds under
ultraviolet irradiation, has traditionally been investigated using animals. However, the …
ultraviolet irradiation, has traditionally been investigated using animals. However, the …
[HTML][HTML] Pathogenesis of Inflammation in Skin Disease: From Molecular Mechanisms to Pathology
SN Shirley, AE Watson, N Yusuf - International Journal of Molecular …, 2024 - mdpi.com
Many skin diseases begin with inflammatory changes on a molecular level. To develop a
more thorough understanding of skin pathology and to identify new targets for therapeutic …
more thorough understanding of skin pathology and to identify new targets for therapeutic …
Neutrophil-derived oxidative stress contributes to skin inflammation and scratching in a mouse model of allergic contact dermatitis via triggering pro-inflammatory …
Y Yang, Y Pan, B Liu, Y Zhang, C Yin, J Wang… - Biochemical …, 2024 - Elsevier
Allergic contact dermatitis (ACD) is a common skin disease featured with skin inflammation
and a mixed itch/pain sensation. The itch/pain causes the desire to scratch, affecting both …
and a mixed itch/pain sensation. The itch/pain causes the desire to scratch, affecting both …
Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin …
Atopic dermatitis, psoriasis and lichen sclerosus are among the most challenging conditions
treated by dermatologists worldwide, with potentially significant physical, social and …
treated by dermatologists worldwide, with potentially significant physical, social and …
Schizonepeta tenuifolia Briq-Saposhnikovia divaricata decoction alleviates atopic dermatitis via downregulating macrophage TRPV1
H Li, J Liang, P Li, X Li, Q Liu, S Yang… - Frontiers in …, 2024 - frontiersin.org
Objective Schizonepeta tenuifolia-Saposhnikovia divaricata (Jingjie-Fangfeng, JF) has been
used for years to treat allergic inflammatory skin diseases like atopic dermatitis, but the …
used for years to treat allergic inflammatory skin diseases like atopic dermatitis, but the …
[HTML][HTML] Proton pump inhibitor alters Th17/Treg balance and induces gut dysbiosis suppressing contact hypersensitivity reaction in mice
A Strzępa, K Marcińska, A Kiecka… - Frontiers in …, 2024 - frontiersin.org
Proton pump inhibitors (PPIs), such as omeprazole, are the most commonly prescribed
drugs. Treatment with PPIs alters gut microbiota composition and reduces the production of …
drugs. Treatment with PPIs alters gut microbiota composition and reduces the production of …
Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model
M Xue, CJ Jackson, H Lin, R Zhao, HPH Liang… - International Journal of …, 2024 - mdpi.com
Endothelial protein C receptor (EPCR) is a receptor for the natural anti-coagulant activated
protein C (aPC). It mediates the anti-inflammatory and barrier-protective functions of aPC …
protein C (aPC). It mediates the anti-inflammatory and barrier-protective functions of aPC …
Aloe-emodin relieves allergic contact dermatitis pruritus by inhibiting mast cell degranulation
Y Yang, J Sun, H You, Y Sun, Y Song, Z Shen, T Liu… - Immunology …, 2024 - Elsevier
Urushiol-induced allergic contact dermatitis (ACD) is a chronic inflammatory skin disease in
which skin barrier dysfunction leads to pruritus and eczematous lesions. ACD is triggered by …
which skin barrier dysfunction leads to pruritus and eczematous lesions. ACD is triggered by …
Advancements in Dermatological Applications of Curcumin: Clinical Efficacy and Mechanistic Insights in the Management of Skin Disorders
Z Mo, J Yuan, X Guan, J Peng - Clinical, Cosmetic and …, 2024 - Taylor & Francis
Curcumin, derived from Curcuma longa (turmeric), exhibits significant potential in
dermatology, addressing conditions like atopic dermatitis, psoriasis, chronic wounds, skin …
dermatology, addressing conditions like atopic dermatitis, psoriasis, chronic wounds, skin …
[HTML][HTML] Causal relationship and mediation effects of immune cells and plasma metabolites in atopic dermatitis: A Mendelian randomization study
K Yang, J Zhong, D Xian - Medicine, 2024 - journals.lww.com
Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex etiology
involving genetic, environmental, and immunological factors. This study employs Mendelian …
involving genetic, environmental, and immunological factors. This study employs Mendelian …