[HTML][HTML] Drug development for autism spectrum disorder (ASD): progress, challenges, and future directions

JT McCracken, E Anagnostou, C Arango… - European …, 2021 - Elsevier
In 2017, facing lack of progress and failures encountered in targeted drug development for
Autism Spectrum Disorder (ASD) and related neurodevelopmental disorders, the ISCTM …

Measurement matters: A commentary on the state of the science on patient reported outcome measures (PROMs) in autism research

HK Schiltz, ZJ Williams, S Zheng… - Autism …, 2024 - Wiley Online Library
High quality science relies upon psychometrically valid and reliable measurement, yet very
few Patient Reported Outcome Measures (PROMs) have been developed or thoroughly …

A lifespan approach to patient‐reported outcomes and quality of life for people on the autism spectrum

L Graham Holmes, CJ Zampella, C Clements… - Autism …, 2020 - Wiley Online Library
Autistic self‐advocates, family members, and community organizations have called for
greater emphasis on enhancing quality of life (QoL) for people with autism. Doing this is …

Post–high school daily living skills in autism spectrum disorder

EB Clarke, JB McCauley, C Lord - Journal of the American Academy of …, 2021 - Elsevier
Objective Daily living skills (DLS) are a predictor of positive outcomes in youths with autism
spectrum disorder (ASD), yet little is known about trajectories of DLS in adults with ASD. This …

Trajectory research in children with an autism diagnosis: A scoping review

SJ Gentles, EC Ng-Cordell, MC Hunsche, AJ McVey… - …, 2024 - journals.sagepub.com
Researchers increasingly employ longitudinal trajectory methods to understand
developmental pathways of people on the autism spectrum across the lifespan. By …

Efficacy of very early interventions on neurodevelopmental outcomes for infants and toddlers at increased likelihood of or diagnosed with autism: a systematic review …

A McGlade, K Whittingham, J Barfoot, L Taylor… - Autism …, 2023 - Wiley Online Library
The aim of this systematic review was to determine the efficacy of very early interventions for
infants and toddlers at increased likelihood of or diagnosed with autism for autism …

Work and well‐being: Vocational activity trajectories in young adults with autism spectrum disorder

EB Clarke, K Sterrett, C Lord - Autism Research, 2021 - Wiley Online Library
Young adults with autism spectrum disorder (ASD) experience limited social connectedness,
difficulty living independently, and other poor outcomes at high rates. Vocational activities …

Mechanisms of change in behavioral activation: Adapting depression treatment for autistic people

VH Bal, E Wilkinson, V Glascock, RP Hastings… - … and behavioral practice, 2023 - Elsevier
Despite high rates of co-occurring depression, few studies have developed or adapted
treatments targeting depressive symptoms for autistic adults. Behavioral activation is widely …

Autism spectrum disorder

LG Klinger, KM Dudley - Treatment of disorders in childhood and …, 2019 - books.google.com
Historically, the primary question for treatment of individuals with autism spectrum disorder
(ASD) has been to identify which is the “best” treatment for this disorder. Initially, then, when …

Trials and Tribulations in Early Autism Intervention Research.

T Charman - Journal of the American Academy of Child and …, 2019 - europepmc.org
Despite a slow start, 1 the past 15 years has seen an unprecedented increase in the number
and quality of randomized controlled trials (RCTs) being conducted in the early autism field …