Unique to striated muscle cells, transverse tubules (t-tubules) are membrane organelles that
consist of sarcolemma penetrating into the myocyte interior, forming a highly branched and …

Heart transplantation is the most effective therapy for patients with Stage D heart failure with
a median life expectancy of≈ 10 to 15 years. Unfortunately, many patients die on the waiting …

The best definitive treatment option for end-stage heart failure currently is transplantation,
which is limited by donor availability and immunorejection. Generating an autologous …

Trends in Organ Donation and Transplantation in the United States, 1999-2008 -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Background—Survival of patients on left ventricular assist devices (LVADs) has improved.
We examined the differences in risk of adverse outcomes between LVAD-supported and …

Lung and heart allocation in the United States has evolved over the past 20–30 years to
better serve transplant candidates and improve organ utilization. The current lung allocation …

BACKGROUND: Left ventricular assist devices (LVADs) have revolutionized the
management of end-stage heart failure (ESHF). However, unexpectedly high rates of GI …

Background—This study evaluated whether minority orthotopic heart transplant (OHT)
recipients tend to be transplanted at worse performing centers. Methods and Results—OHT …

BACKGROUND The new heart allocation system in the United States prioritizes patients
supported by temporary mechanical circulatory support (TMCS) devices over those with …

Background—A change in allocation algorithm in July 2006 allowed broader regional
sharing of donor hearts in the United States (US). We assessed if the allocation change has …