[HTML][HTML] Alcohol-associated liver disease

B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

[HTML][HTML] Hepatic mitochondrial reductive stress in the pathogenesis and treatment of steatotic liver disease

MJ Jokinen, PK Luukkonen - Trends in Pharmacological Sciences, 2024 - cell.com
Steatotic liver diseases (SLDs) affect one-third of the population, but the pathogenesis
underlying these diseases is not well understood, limiting the available treatments. A …

Validation of the new nomenclature of steatotic liver disease in patients with a history of excessive alcohol intake: an analysis of data from a prospective cohort study

M Israelsen, N Torp, S Johansen… - The Lancet …, 2024 - thelancet.com
Background Steatotic liver disease is a new overarching term that includes metabolic
dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol …

[HTML][HTML] Association between public health policies on alcohol and worldwide cancer, liver disease and cardiovascular disease outcomes

LA Díaz, E Fuentes-López, F Idalsoaga, G Ayares… - Journal of …, 2024 - Elsevier
Background & Aims The long-term impact of alcohol-related public health policies (PHPs) on
disease burden is unclear. We aimed to assess the association between alcohol-related …

From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research

CL Hsu, R Loomba - Nature Metabolism, 2024 - nature.com
Non-alcoholic liver disease (NAFLD) is now metabolic dysfunction-associated steatotic liver
disease (MASLD), emphasizing the key metabolic factors of obesity, insulin resistance …

[HTML][HTML] Overexpression of interleukin-8 promotes the progression of fatty liver to nonalcoholic steatohepatitis in mice

YE Cho, Y Kim, SJ Kim, H Lee, S Hwang - International Journal of …, 2023 - mdpi.com
Nonalcoholic steatohepatitis (NASH) is an advanced stage of fatty liver disease
characterized by liver damage, inflammation, and fibrosis. Although neutrophil infiltration is …

Unveiling the cancer risk nexus of the steatotic liver

J Kim, E Seki - Trends in Endocrinology & Metabolism, 2024 - cell.com
Steatotic liver, characterized by the accumulation of fat in the liver, poses significant health
risks including metabolic dysfunction-associated steatotic liver disease (MASLD) and an …

[HTML][HTML] MASLD treatment—a shift in the paradigm is imminent

MV Machado - Frontiers in Medicine, 2023 - frontiersin.org
MASLD prevalence is growing towards the leading cause of end-stage liver disease. Up to
today, the most effective treatment is weight loss. Weight loss interventions are moving from …

Promoting In Vivo NIR-II Fluorescent Imaging for Lipid in Lipid Metabolism Diseases Diagnosis

K Wang, XL Wen, XY Chen, Y Yue, YS Yang… - Analytical …, 2024 - ACS Publications
Lipid metabolism diseases have become a tremendous risk worldwide, along with the
development of productivity and particular attention to public health. It has been an urgent …

Prevalence of at‐risk MASH, M et ALD and alcohol‐associated steatotic liver disease in the general population

CV Schneider, KM Schneider, A Raptis… - Alimentary …, 2024 - Wiley Online Library
Background The prevalence of at‐risk metabolic dysfunction‐associated steatohepatitis (at‐
risk MASH) has not been systematically assessed. Aim To delineate the prevalence of at …