[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …
and can accelerate diabetes-related microvascular and macrovascular complications by …
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nonviral platform for
mRNA delivery. While they have been explored for applications including vaccines and …
mRNA delivery. While they have been explored for applications including vaccines and …
The role of inflammation in the pathogenesis of preeclampsia
M Michalczyk, A Celewicz, M Celewicz… - Mediators of …, 2020 - Wiley Online Library
Preeclampsia (PE) affects 5‐8% of pregnant women, and it is the major cause of perinatal
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …
The placenta in fetal growth restriction: what is going wrong?
The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
[Retracted] Irisin Attenuates Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in the H9C2 Cellular Model of Septic Cardiomyopathy through Augmenting …
X Jiang, S Cai, Y Jin, F Wu, J He, X Wu… - Oxidative Medicine …, 2021 - Wiley Online Library
In the present study, we used lipopolysaccharide‐(LPS‐) stimulated H9C2 cardiomyocytes
to investigate whether irisin treatment attenuates septic cardiomyopathy via Fundc1‐related …
to investigate whether irisin treatment attenuates septic cardiomyopathy via Fundc1‐related …
Orthogonal design of experiments for engineering of lipid nanoparticles for mRNA delivery to the placenta
During healthy pregnancy, the placenta develops to allow for exchange of nutrients and
oxygen between the mother and the fetus. However, placental dysregulation can lead to …
oxygen between the mother and the fetus. However, placental dysregulation can lead to …
[HTML][HTML] Delivery technologies for women's health applications
The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
[HTML][HTML] Modelling human placental villous development: designing cultures that reflect anatomy
JL James, A Lissaman, YNS Nursalim… - Cellular and Molecular …, 2022 - Springer
The use of in vitro tools to study trophoblast differentiation and function is essential to
improve understanding of normal and abnormal placental development. The relative …
improve understanding of normal and abnormal placental development. The relative …