Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities
MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
[HTML][HTML] Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review
Electrical stimulation (ES) shows promise as a therapy to promote recovery and
regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) …
regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) …
Schwann cell-derived exosomal vesicles: a promising therapy for the injured spinal cord
M Ghosh, DD Pearse - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are nanoscale-sized membrane vesicles released by cells into their extracellular
milieu. Within these nanovesicles reside a multitude of bioactive molecules, which …
milieu. Within these nanovesicles reside a multitude of bioactive molecules, which …
[HTML][HTML] Sensory-motor coupling electrical stimulation driven by a bionic Z‐structured triboelectric nanogenerator improves functional recovery from spinal cord injury
B Lu, S Jia, Z Wang, W Wu, L Yan, L Zhu, D Hao - Nano Energy, 2023 - Elsevier
Spinal cord injury (SCI) disrupts the neuronal relay circuits and causes limb paralysis.
Although epidural electrical stimulation is a therapeutic approach for SCI, electrical …
Although epidural electrical stimulation is a therapeutic approach for SCI, electrical …
Rehabilitation training after spinal cord injury affects brain structure and function: From mechanisms to methods
LW He, XJ Guo, C Zhao, JS Rao - Biomedicines, 2023 - mdpi.com
Spinal cord injury (SCI) is a serious neurological insult that disrupts the ascending and
descending neural pathways between the peripheral nerves and the brain, leading to not …
descending neural pathways between the peripheral nerves and the brain, leading to not …
Research progress on the application of transcranial magnetic stimulation in spinal cord injury rehabilitation: a narrative review
Y Wang, T Dong, X Li, H Zhao, L Yang, R Xu… - Frontiers in …, 2023 - frontiersin.org
Traumatic or non-traumatic spinal cord injury (SCI) can lead to severe disability and
complications. The incidence of SCI is high, and the rehabilitation cycle is long, which …
complications. The incidence of SCI is high, and the rehabilitation cycle is long, which …
[HTML][HTML] Established and emerging therapies in acute spinal cord injury
Acute spinal cord injury (SCI) is devastating for patients and their caretakers and has an
annual incidence of 20–50 per million people. Following initial assessment with appropriate …
annual incidence of 20–50 per million people. Following initial assessment with appropriate …
Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes axon growth
J Wu, ZY Zhu, ZW Fan, Y Chen… - Neural Regeneration …, 2022 - journals.lww.com
The rapid formation of a glial/fibrotic scar is one of the main factors hampering axon growth
after spinal cord injury. The bidirectional EphB2/ephrin-B2 signaling of the fibroblast …
after spinal cord injury. The bidirectional EphB2/ephrin-B2 signaling of the fibroblast …