The crosstalk among the complement system, immune cells, and mediators of inflammation
provides an efficient mechanism to protect the organism against infections and support the …

Perivascular niches in the kidney comprise heterogeneous cell populations, including
pericytes and fibroblasts, with distinct functions. These perivascular cells have crucial roles …

A small fraction of people vaccinated with mRNA–lipid nanoparticle (mRNA-LNP)-based
COVID-19 vaccines display acute or subacute inflammatory symptoms whose mechanism …

Cadmium (Cd), a serious environmental contaminant, is associated with adverse health
effects. However, the specific changes that the human body experiences in response to …

Among the broad spectrum of membranoproliferative glomerulonephritis (MPGN),
immunofluorescence distinguishes C3 glomerulopathy (C3G), with predominant C3 …

Combination therapy with glucocorticoids, cyclophosphamide, and plasmapheresis is
recommended as the standard treatment for anti-glomerular basement membrane (anti …

The complement system, an important part of the innate system, is known to play a central
role in many immune mediated kidney diseases. All parts of the complement system …

Podocytes are the key target cells for injury across the spectrum of primary and secondary
proteinuric kidney disorders, which account for up to 90% of cases of kidney failure …

Nephrology is an ever-evolving field of medicine. The importance of such a discipline is
related to the high clinical impact of kidney disease. In fact, abnormalities of kidney function …

Background Microangiopathy (MA) lesions are not rare in immunoglobulin A nephropathy
(IgAN) and have been suggested to have a potential role in increasing risk in renal function …