Liver cirrhosis is a major cause of mortality worldwide, often with severe sepsis as the
terminal event. Over the last two decades, several studies have reported that in septic …

Background Critically ill patients often require emergency intubation. The use of etomidate
as the sedative agent in this context has been challenged because it might cause a …

BACKGROUND: Community-acquired pneumonia (CAP) is pneumonia acquired infectiously
from normal social contact as opposed to being acquired during hospitalization. CAP is a …

Rationale Use of etomidate in the critically ill is controversial due to its links with an
inadequate response to corticotropin and potential for excess mortality. In a septic shock …

Background—Although some professional societies recommend target-driven glucose
control for all hospitalized patients, the association between elevated glucose and adverse …

Introduction Endotracheal intubation in the ICU is associated with a high incidence of
complications. Etomidate use is debated in septic shock because it increases the risk of …

OBJECTIVES: Our aim was to review the literature on the prevalence and impact of critical-
illness related corticosteroid insufficiency (CIRCI) on the outcomes of patients with severe …

Despite increased cortisol production, adrenal function may be disturbed, and exogenous
ACTH (cosyntropin) may result in little or no cortisol synthesis. 20, 21 Relative adrenal …

Adrenal insufficiency following traumatic brain injury in ad... : Current Opinion in Critical Care
Adrenal insufficiency following traumatic brain injury in adults : Current Opinion in Critical Care …

A central feature of the endocrine pathophysiology of septic shock is thought to be the
existence of adrenal dysfunction. Based on changes in glucocorticoid secretion and …