IApproximately 30% of patients with chronic HCV infection have persistently normal alanine
aminotransferase levels (PNALT). Most of these patients have minimal or mild inflammation …

The purpose of this study was to investigate vascular preconditioning of individual
microvascular networks. Prior work shows that exposure of downstream arterioles to specific …

Intercellular communication through gap junction channels plays a fundamental role in
regulating vascular myocyte tone. We investigated gap junction channel expression and …

Since cytochrome P450‐derived metabolites of arachidonic acid and K+ have been
implicated in endothelium‐derived hyperpolarizing factor (EDHF)‐dependent responses, the …

Diffusion-mediated changes in ion channel function within blood vessels have not been
demonstrated directly in a patch-clamp study. Here, we examined the hypothesis that …

Phenotypic variability in smooth muscle cells accounts, in large part, for the incredible
functional diversity required of the involuntary hollow organs of the body (ie, respiratory …

The aim of the present study was to determine the relative contribution of prostanoids, nitric
oxide and K+ channels in the bradykinin‐induced relaxation of bovine pulmonary …

To understand blood pressure is regulated, and how this regulation is disturbed in
hypertension, we need to understand how blood volume is regulated and how the …

The invention relates to the permeability of gap junctions and Specifically to agents which
modulate same. The inven tion describes the use of cAMP and/or cAMP phosphodi esterase …

Background Gap junction intercellular communication plays a fundamental role in various
tissues and organs. Gap junctions transfer ions and molecules between adjacent cells and …