There is now strong evidence that an endothelial mechanism, other than nitric oxide or
prostacyclin, exists for dilating arteries and arterioles. This third pathway has been named …

The possibility that stimulation of smooth muscle α1‐adrenoceptors modulates contraction
via the endothelium was examined in rat small mesenteric arteries. Nω‐nitro‐l‐arginine …

The vascular endothelium is strategically located between the circulating blood and the
vascular smooth muscle cells. Different agonists or stimuli transported by the circulating …

The present study evaluated the role of endothelial intermediate conductance calcium-
sensitive potassium channels (IKCa) in the mechanism of endothelium-derived …

The effect of peptides with sequences derived from connexins, the constituent proteins of
gap junctions, on mechanically stimulated intercellular Ca2+ signaling in tracheal airway …

Gap junctions are key components underpinning multicellularity. They provide cell to cell
channel pathways that enable direct intercellular communication and cellular coordination in …

Abstract Connexin 43 (Cx43) is essential to the function of the vasculature. Cx43 proteins
form gap junctions that allow for the exchange of ions and molecules between vascular cells …

Vascular resistance networks control tissue blood flow in concert with regulating arterial
perfusion pressure. In response to increased metabolic demand, vasodilation arising in …

Synthetic peptides homologous to the Gap 26 and Gap 27 domains of the first and second
extracellular loops of the major vascular connexins (Cx37, Cx40, and Cx43) have been used …

In the epidermis, remodelling of Connexin43 is a key event in wound closure. However,
controversy between the role of connexin channel and non-channel functions exist. We …