In isolated superior mesenteric artery rings from age-matched control rats and streptozotocin
(STZ)-induced diabetic rats, we investigated the role of cAMP in endothelium-derived …

Migration of lymphocytes across the endothelium of central or peripheral tissues, a process
occurring following activation or differentiation, involves cell to cell interactions featuring …

Although an endothelium-derived hyperpolarizing factor (EDHF) has often been
hypothesized to underpin vascular relaxations that are independent of nitric oxide (NO) and …

Smooth muscle membrane potential and tension in rat isolated small mesenteric arteries
(inner diameter 100–200 μm) were measured simultaneously to investigate whether the …

Arterioles within the microcirculation control organ blood flow and represent the main
peripheral resistance within the circulation. However, larger vessels with a diameter of more …

In the vessel wall, endothelial cells are metabolically and electrically coupled to each other
and to the adjacent smooth muscle cells by gap junctions composed of connexins. Gap …

Effects of connexin-mimetic peptides on nitric oxide synthase-and cyclooxygenase-
independent renal vasodilation. Background Research on the physiological role of …

Intercellular communication between cells within the blood vessel wall plays an important
role in the control of artery diameter. The endothelial cells lining the lumen of arteries can …

1. PREFACE This thesis is based on the work carried in the Vascular Smooth Muscle group
at the Institute of Physiology and Biophysics, Aarhus University. This thesis is focused on a …

Background Bone remodelling is dependent on the balance between bone resorbing
osteoclasts and bone forming osteoblasts. We have shown previously that osteoclasts …