IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice

Z Qu, W Dou, K Zhang, L Duan, D Zhou… - Arthritis Research & …, 2022 - Springer
Background Interstitial lung disease, a common extra-articular complication of connective
tissue disease, is characterized by progressive and irreversible pulmonary inflammation and …

Evaluation of the amelioration effect of Ganoderma formosanum extract on delaying PM2.5 damage to lung macrophages

CY Hou, CC Hsieh, YC Hung, CC Hsu… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Particulate matter (PM) contains toxic organic matter and heavy metals that enter the
entire body through blood flow and may cause mortality. Ganoderma formosanum mycelium …

The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation

N Madbouly, A Azmy, A Salama, A El-Amir - The Journal of Antibiotics, 2021 - nature.com
Amikacin (AMK) is one of the most effective aminoglycoside antibiotics. However,
nephrotoxicity is a major deleterious and dose-limiting side effect associated with its clinical …

Hues of risk: investigating genotoxicity and environmental impacts of azo textile dyes

K Ramamurthy, PS Priya, R Murugan… - … Science and Pollution …, 2024 - Springer
The textile industry, with its extensive use of dyes and chemicals, stands out as a significant
source of water pollution. Exposure to certain textile dyes, such as azo dyes and their …

Monitoring regulatory T cells as a prognostic marker in lung transplantation

MA Khan, CL Lau, AS Krupnick - Frontiers in Immunology, 2023 - frontiersin.org
Lung transplantation is the major surgical procedure, which restores normal lung functioning
and provides years of life for patients suffering from major lung diseases. Lung transplant …

Alginate/gelatin/boron-doped hydroxyapatite-coated Ti implants: in vitro and in vivo evaluation of osseointegration

AE Pazarceviren, Z Evis, T Dikmen, K Altunbaş… - Bio-Design and …, 2023 - Springer
In this study, boron-doped hydroxyapatite (BHT)-loaded alginate/gelatin-based (A/G)
hydrogel coating on Ti was fabricated to support bone integration through triggering …

Higher susceptibility of males to bleomycin-induced pulmonary inflammation is associated with sex-specific transcriptomic differences in myeloid cells

R Lamichhane, S Patial, Y Saini - Toxicology and applied pharmacology, 2022 - Elsevier
Idiopathic pulmonary fibrosis, a condition with likely genetic and environmental etiology, is
relatively more prevalent with poor prognosis in human males. However, the underlying …

Crosstalk between estrogen, dendritic cells, and SARS‐CoV‐2 infection

D Mateus, AI Sebastião, MA Carrascal… - Reviews in Medical …, 2022 - Wiley Online Library
The novel coronavirus disease 2019 (Covid‐19) first appeared in Wuhan and has so far
killed more than four million people worldwide. Men are more affected than women by Covid …

Parotid glands have a dysregulated immune response following radiation therapy

JA Gunning, KE Gilman, TM Zúñiga, RJ Simpson… - Plos one, 2024 - journals.plos.org
Head and neck cancer treatment often consists of surgical resection of the tumor followed by
ionizing radiation (IR), which can damage surrounding tissues and cause adverse side …

The mast cell: A Janus in kidney transplants

G van der Elst, H Varol, M Hermans, CC Baan… - Frontiers in …, 2023 - frontiersin.org
Mast cells (MCs) are innate immune cells with a versatile set of functionalities, enabling
them to orchestrate immune responses in various ways. Aside from their known role in …