Osteochondral organoids: current advances, applications, and upcoming challenges

M Faeed, M Ghiasvand, B Fareghzadeh… - Stem Cell Research & …, 2024 - Springer
In the realm of studying joint-related diseases, there is a continuous quest for more accurate
and representative models. Recently, regenerative medicine and tissue engineering have …

Intra-articular bone marrow mononuclear cell therapy improves lameness from naturally occurring equine osteoarthritis

JB Everett, BC Menarim, SH Barrett… - Frontiers in Veterinary …, 2023 - frontiersin.org
Osteoarthritis (OA) can be debilitating and is related to impaired resolution of synovial
inflammation. Current treatments offer temporary relief of clinical signs, but have potentially …

Discovery and functional characterization of LncRNAs associated with inflammation and macrophage activation

A Chini, P Guha, A Rishi, M Obaid, SMN Udden… - Methods, 2024 - Elsevier
Long noncoding RNAs (lncRNA) are emerging players in regulation of gene expression and
cell signaling and their dysregulation has been implicated in a multitude of human diseases …

转化生长因子-β 参与骨骼肌损伤修复的机制探讨及研究进展.

宋宁静, 周晶, 曹必伟, 赵焰, 余韵扬… - Journal of Practical …, 2024 - search.ebscohost.com
骨骼肌损伤是临床上常见的疾病, 对其修复机制的深入了解对于制定有效的治疗策略至关重要.
本文聚焦于TGF-β 在骨骼肌损伤修复中的关键作用, 介绍了其家族成员的多样性和信号传导途径 …

Magnetic nanomagnetic nanoparticles combining with Slit2 gene and bone marrow mononuclear cells to improve cognitive dysfunction in rats with chronic cerebral …

N Wang, M Lin, W Guo, Y Cao - International Journal of Medical …, 2024 - medsci.org
Purpose: Cognitive dysfunction caused by chronic cerebral hypoperfusion (CCH) is the
leading cause of vascular dementia. Therefore, it is necessary to explore the mechanism …

Downhill Running Increases Bone Mass Accumulation and Bone Tissues Morphology through the TGF-β/Smad Pathway in the Bone of Growing Mice

X Chen, P Sun, A Chen, H Peng, X Zhang, K Yang… - 2023 - researchsquare.com
Background: Substantial evidence has demonstrated that impact exercise can help
adolescents to accumulate more bone mass. However, the effect of OB (osteoblast) on …