Diabetic foot ulcers (DFU) are a serious complication of diabetes mellitus and associated
with reduced quality of life and high mortality rate. DFUs are characterized by a deregulated …

Persistent and impaired inflammation impedes tissue healing and is a characteristic of
chronic wounds. A better understanding of the mechanisms controlling wound inflammation …

Diabetic foot ulcers are a common complication of diabetes, and are usually incurable in the
clinic. Exosomes (carriers that transfer endogenous molecules) from diabetic patients' blood …

Stringent spatiotemporal regulation of the wound healing process involving multiple cell
types is associated with epigenetic mechanisms of gene regulation, such as DNA …

Background Diabetic foot ulcer (DFU), persistent hyperglycemia and inflammation, together
with impaired nutrient and oxygen deficiency, can present abnormal angiogenesis following …

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by
recurrent abscesses, nodules, and sinus tracts in areas of high hair follicle and sweat gland …

Perforin-2 (P-2) is an antimicrobial protein with unique properties to kill intracellular bacteria.
Gamma delta (GD) T cells, as the major T cell population in epithelial tissues, play a central …

Diabetes mellitus (DM) is a group of metabolic diseases marked by hyperglycemia, which
increases the risk of systemic infections. DM patients are at greater risk of hospitalization …

Breach of the skin barrier and subsequent wound healing occur in the context of microbial
communities of bacteria, fungi, and viruses. These polymicrobial communities are dynamic …

Non-coding RNA (ncRNA) is a special type of RNA transcript that makes up more than 90%
of the human genome. Although ncRNA typically does not encode proteins, it indirectly …