Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of …
The classical examination of histology slides from a mouse model of breast cancer has been
extended in this study to incorporate modern multiphoton excitation and photon-counting …
extended in this study to incorporate modern multiphoton excitation and photon-counting …
[HTML][HTML] Simultaneous NAD (P) H and FAD fluorescence lifetime microscopy of long UVA–induced metabolic stress in reconstructed human skin
Solar ultraviolet longwave UVA1 exposure of human skin has short-term consequences at
cellular and molecular level, leading at long-term to photoaging. Following exposure …
cellular and molecular level, leading at long-term to photoaging. Following exposure …
[HTML][HTML] Efficacy of artificial intelligence-assisted discrimination of oral cancerous lesions from normal mucosa based on the oral mucosal image: a systematic review …
JS Kim, BG Kim, SH Hwang - Cancers, 2022 - mdpi.com
Simple Summary Early detection of oral cancer is important to increase the survival rate and
reduce morbidity. For the past few years, the early detection of oral cancer using artificial …
reduce morbidity. For the past few years, the early detection of oral cancer using artificial …
Multiphoton redox ratio imaging for metabolic monitoring in vivo
M Skala, N Ramanujam - Advanced Protocols in Oxidative Stress II, 2010 - Springer
Metabolic monitoring at the cellular level in live tissues is important for understanding cell
function, disease processes, and potential therapies. Multiphoton imaging of the relative …
function, disease processes, and potential therapies. Multiphoton imaging of the relative …
In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH
MA Yaseen, S Sakadžić, W Wu, W Becker… - Biomedical optics …, 2013 - opg.optica.org
Minimally invasive, specific measurement of cellular energy metabolism is crucial for
understanding cerebral pathophysiology. Here, we present high-resolution, in vivo …
understanding cerebral pathophysiology. Here, we present high-resolution, in vivo …
[HTML][HTML] Label-free non-linear multimodal optical microscopy—basics, development, and applications
Non-linear optical (NLO) microscopy has proven to be a powerful tool especially for tissue
imaging with sub-cellular resolution, high penetration depth, endogenous contrast …
imaging with sub-cellular resolution, high penetration depth, endogenous contrast …
[HTML][HTML] Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics
Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet,
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …
Dicyanoisophorone-based near-infrared-emission fluorescent probe for detecting NAD (P) H in living cells and in vivo
Y Zhao, K Wei, F Kong, X Gao, K Xu, B Tang - Analytical chemistry, 2018 - ACS Publications
NADH and NADPH are ubiquitous coenzymes in all living cells that play vital roles in
numerous redox reactions in cellular energy metabolism. To accurately detect the …
numerous redox reactions in cellular energy metabolism. To accurately detect the …
Label-free characterization of white blood cells using fluorescence lifetime imaging and flow-cytometry: molecular heterogeneity and erythrophagocytosis
BP Yakimov, MA Gogoleva, AN Semenov… - Biomedical optics …, 2019 - opg.optica.org
Blood cell analysis is one of the standard clinical tests. Despite the widespread use of
exogenous markers for blood cell quantification, label-free optical methods are still of high …
exogenous markers for blood cell quantification, label-free optical methods are still of high …
Wide-field fluorescence lifetime imaging of cancer
J McGinty, NP Galletly, C Dunsby, I Munro… - Biomedical optics …, 2010 - opg.optica.org
Optical imaging of tissue autofluorescence has the potential to provide rapid label-free
screening and detection of surface tumors for clinical applications, including when combined …
screening and detection of surface tumors for clinical applications, including when combined …