Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global
health. Correlating with liver disease progression, fibrosis is a key factor for liver disease …

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …

Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …

Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …

The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and NAFLD‐related
cirrhosis in the United States and globally highlights the need to better understand the …

Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it remains still orphan of an adequate therapeutic …

Inflammation and hepatocyte injury and death are the hallmarks of nonalcoholic
steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease (NAFLD) …

Aging is a complex phenomenon characterized by the progressive loss of tissue and organ
function. The oxidative-stress theory of aging postulates that age-associated functional …