Cancer heterogeneity and drug resistance remain pivotal obstacles in effective cancer
treatment and management. One major contributor to these challenges is epigenetic …

RNA methylation, an epigenetic modification that does not alter gene sequence, may be
important to diverse biological processes. Protein regulators of RNA methylation include …

Endometrial cancer (EC) is a prevalent gynecological malignancy worldwide, and 5-
methylcytosine (m 5 C) modification of mRNA is a crucial epigenetic modification associated …

Glioma is a type of aggressive and incurable brain tumor. Patients with glioma are highly
resistant to all types of therapies, including immunotherapies. Epigenetic reprogramming is …

Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous tumor comprising
pancreatic cancer cells, fibroblasts, immune cells, vascular epithelial cells, and other cells in …

Immunogenic-and immune-therapies have become hot spots in the treatment of cancer.
Although promising, these strategies are frequently associated with innate or acquired …

Simple Summary Cancer treatments have made remarkable advances with the introduction
of immunotherapy, which recruits the body's immune system to fight cancer. Despite these …

Not only genetic but also epigenetic factors are closely associated with cancer, especially
with its malignant evolution. Cancer therapies based on epigenetic modulation have …

Traditionally, it has been believed that inheritance is driven as phenotypic variations
resulting from changes in DNA sequence. However, this paradigm has been challenged and …

Colorectal cancer (CRC) is a complex disease characterized by genetic and epigenetic
alterations, playing a crucial role in its development and progression. This review aims to …