Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

JR Huddleston - Infection and drug resistance, 2014 - Taylor & Francis
Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic
resistance among pathogens. This review aims to give an overview of the major horizontal …

Acinetobacter baumannii: Emergence of a Successful Pathogen

AY Peleg, H Seifert, DL Paterson - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation

S Fulsundar, K Harms, GE Flaten… - Applied and …, 2014 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are continually released from a range of bacterial species.
Numerous functions of OMVs, including the facilitation of horizontal gene transfer (HGT) …

Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species

S Domingues, K Harms, WF Fricke, PJ Johnsen… - 2012 - journals.plos.org
We have investigated to what extent natural transformation acting on free DNA substrates
can facilitate transfer of mobile elements including transposons, integrons and/or gene …

Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1

I Pardo, RK Jha, RE Bermel, F Bratti, M Gaddis… - Metabolic …, 2020 - Elsevier
Microbial terephthalic acid (TPA) catabolic pathways are conserved among the few bacteria
known to turnover this xenobiotic aromatic compound. However, to date there are few …

Systems biology of competency in Vibrio natriegens is revealed by applying novel data analytics to the transcriptome

J Shin, K Rychel, BO Palsson - Cell Reports, 2023 - cell.com
Vibrio natriegens regulates natural competence through the TfoX and QstR transcription
factors, which are involved in external DNA capture and transport. However, the extensive …

Bacterial recombination promotes the evolution of multi-drug-resistance in functionally diverse populations

GG Perron, AEG Lee, Y Wang… - … of the Royal …, 2012 - royalsocietypublishing.org
Bacterial recombination is believed to be a major factor explaining the prevalence of multi-
drug-resistance (MDR) among pathogenic bacteria. Despite extensive evidence for …

NATURAL TRANSFORMATION INCREASES THE RATE OF ADAPTATION IN THE HUMAN PATHOGEN HELICOBACTER PYLORI

DA Baltrus, K Guillemin, PC Phillips - Evolution, 2008 - academic.oup.com
Gene exchange between individuals can lead to profound evolutionary effects at both the
genomic and population levels. These effects have sparked widespread interest in …

The population and evolutionary dynamics of homologous gene recombination in bacteria

BR Levin, OE Cornejo - PLoS genetics, 2009 - journals.plos.org
In bacteria, recombination is a rare event, not a part of the reproductive process.
Nevertheless, recombination—broadly defined to include the acquisition of genes from …

Horizontal Gene Transfer, Fitness Costs and Mobility Shape the Spread of Antibiotic Resistance Genes into Experimental Populations of Acinetobacter Baylyi

AL Sezmis, LC Woods, AY Peleg… - Molecular Biology and …, 2023 - academic.oup.com
Horizontal gene transfer (HGT) is important for microbial evolution, but how evolutionary
forces shape the frequencies of horizontally transferred genetic variants in the absence of …