[HTML][HTML] Genomics of Wolfram Syndrome 1 (WFS1)

S Kõks - Biomolecules, 2023 - mdpi.com
Wolfram Syndrome (WFS) is a rare, autosomal, recessive neurogenetic disorder that affects
many organ systems. It is characterised by diabetes insipidus, diabetes mellites, optic …

Clinical pharmacology of cardiac cyclic AMP in human heart failure: too much or too little?

A Lymperopoulos - Expert Review of Clinical Pharmacology, 2023 - Taylor & Francis
ABSTRACT Introduction Cyclic 3', 5'-adenosine monophosphate (cAMP) is a major signaling
hub in cardiac physiology. Although cAMP signaling has been extensively studied in cardiac …

Direct modulation of G protein-gated inwardly rectifying potassium (GIRK) channels

H Nguyen, IW Glaaser, PA Slesinger - Frontiers in Physiology, 2024 - frontiersin.org
Ion channels play a pivotal role in regulating cellular excitability and signal transduction
processes. Among the various ion channels, G-protein-coupled inwardly rectifying …

[HTML][HTML] Neural mechanism facilitating PM2. 5-related cardiac arrhythmias through cardiovascular autonomic and calcium dysregulation in a rat model

TY Tsai, LW Lo, WL Lin, YH Chou, WH Cheng… - Scientific reports, 2023 - nature.com
Abstract Particulate matter< 2.5 μm (PM2. 5) exposure is associated with increased
arrhythmia events and cardiovascular mortality, but the detailed mechanism remained …

Screening of the Key Genes and Signaling Pathways for Schizophrenia Using Bioinformatics and Next Generation Sequencing Data Analysis

BM Vastrad, CM Vastrad - bioRxiv, 2023 - biorxiv.org
Schizophrenia is thought to be the most prevalent chronic psychiatric disorder. Numerous
proteins have been identified that are associated with the occurrence and development of …