In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the
necrosis of tumors, but it has been recently identified to have additional important functions …

Autoimmune disorders are characterized as a condition in which the host's immune system
mistakenly attacks itself. These disorders cause the immune system to cause a systemic …

Sulfoximines have been largely disregarded in medicinal chemistry for a long time.
However, recently, they have risen to the apparent level of stardom on the drug discovery …

Psoriasis is an immune cell-mediated inflammatory skin disease. The interleukin (IL) 23/IL17
axis plays an important role in the development of psoriasis. The effectiveness of biologic …

Psoriasis is a common, chronic, and recurrent inflammatory disease. It is characterized by
hyperproliferation and abnormal differentiation of keratinocytes. Keratinocyte death is also …

Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …