The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

Cataract, defined as the opacification of the lens that prevents clear vision, is a leading
cause of vision loss and impairment worldwide. Elderly people comprise the highest …

Aim To explore the trends in the prevalence and disease burden of cataract from 1990 to
2019, evaluate attributable risk factors, and predict trends over the next decade in China and …

Ocular drug delivery is a challenging but fascinating topical route of administration. Although
the eye is easily accessible to common drug formulations such as drops, its complex …

Abstract Background/Objectives Cataract surgery with intraocular lens (IOL) implantation is
one of the most commonly performed surgeries worldwide. Within the UK, publicly funded …

Cataract is a leading cause of blindness globally, and its surgical treatment poses a
significant burden on global healthcare. Pharmacologic therapies, including antioxidants …

PURPOSE To evaluate the safety and efficacy of non-steroidal anti-inflammatory drugs
(NSAIDs) and corticosteroids in the postoperative management of cataract surgery for age …

Ultraviolet B (UVB) exposure is reported to cause cataract formation by inducing excessive
reactive oxygen species (ROS) and apoptosis in human lens epithelial cells (HLECs) …

A sharp drop in lenticular glutathione (GSH) plays a pivotal role in age-related cataract
(ARC) formation. Despite recognizing GSH's importance in lens defense for decades, its …

Molecular hydrogen (H2) is a colorless, odorless, and tasteless gas which displays non-toxic
features at high concentrations. H2 can alleviate oxidative damage, reduce inflammatory …