Tendinopathy

NL Millar, KG Silbernagel, K Thorborg… - Nature reviews Disease …, 2021 - nature.com
Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair

V Citro, M Clerici, AR Boccaccini… - Journal of tissue …, 2023 - journals.sagepub.com
Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Achilles tendinopathy pathogenesis and management: a narrative review

D Tarantino, R Mottola, G Resta, R Gnasso… - International Journal of …, 2023 - mdpi.com
The Achilles tendon is the thickest and strongest tendon of the human body, and it is
frequently injured during sports activity. The incidence of Achilles tendon pathologies has …

[HTML][HTML] The tendon microenvironment: Engineered in vitro models to study cellular crosstalk

M Gomez-Florit, CJ Labrador-Rached… - Advanced Drug Delivery …, 2022 - Elsevier
Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …

Patellar tendinopathy: an overview of prevalence, risk factors, screening, diagnosis, treatment and prevention

A Theodorou, G Komnos, M Hantes - Archives of Orthopaedic and Trauma …, 2023 - Springer
Patellar tendinopathy (PT), or jumper's knee, is an overuse injury that occurs in professional,
as well as recreational, athletes. This condition is a noncontact injury, typically characterized …

Efficacy of low-level laser therapy in patients with lower extremity tendinopathy or plantar fasciitis: systematic review and meta-analysis of randomised controlled trials

IF Naterstad, J Joensen, JM Bjordal, C Couppé… - BMJ open, 2022 - bmjopen.bmj.com
Objectives We investigated the effectiveness of low-level laser therapy (LLLT) in lower
extremity tendinopathy and plantar fasciitis on patient-reported pain and disability. Design …

CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition

Y Cho, HS Kim, D Kang, H Kim, N Lee, J Yun… - Science …, 2021 - science.org
Tendinopathy, the most common disorder affecting tendons, is characterized by chronic
disorganization of the tendon matrix, which leads to tendon tear and rupture. The goal was …

Farrerol alleviates collagenase‐induced tendinopathy by inhibiting ferroptosis in rats

Y Wu, J Qian, K Li, W Li, W Yin… - Journal of cellular and …, 2022 - Wiley Online Library
Tendinopathy is mainly characterized by local pain, functional limitation and decreased
athletic ability, which seriously affects the quality of life of patients and the career of athletes …

Therapeutic effects of platelet-derived extracellular vesicles in a bioengineered tendon disease model

AL Graça, RMA Domingues, I Calejo… - International Journal of …, 2022 - mdpi.com
Tendon injuries represent over 30–50% of musculoskeletal disorders worldwide, yet the
available therapies do not provide complete tendon repair/regeneration and full functionality …

Tendon pain–what are the mechanisms behind it?

PW Ackermann, MA Alim, G Pejler… - Scandinavian Journal of …, 2023 - degruyter.com
Objectives Management of chronic tendon pain is difficult and controversial. This is due to
poor knowledge of the underlying pathophysiology of chronic tendon pain, priorly known as …