[HTML][HTML] MicroRNA-based discovery of biomarkers, therapeutic targets, and repositioning drugs for breast cancer
Q Ye, RA Raese, D Luo, J Feng, W Xin, C Dong, Y Qian… - Cells, 2023 - mdpi.com
Breast cancer treatment can be improved with biomarkers for early detection and
individualized therapy. A set of 86 microRNAs (miRNAs) were identified to separate breast …
individualized therapy. A set of 86 microRNAs (miRNAs) were identified to separate breast …
Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review
Y Xu, Z Hong, S Yu, R Huang, K Li, M Li, S Xie… - Oncology …, 2024 - frontiersin.org
SLC25A26 is the only known human mitochondrial S-adenosylmethionine carrier encoding
gene. Recent studies have shown that SLC25A26 is abnormally expressed in some …
gene. Recent studies have shown that SLC25A26 is abnormally expressed in some …
[HTML][HTML] Multi-omics immune interaction networks in lung cancer tumorigenesis, proliferation, and survival
Q Ye, J Hickey, K Summers, B Falatovich… - International journal of …, 2022 - mdpi.com
There are currently no effective biomarkers for prognosis and optimal treatment selection to
improve non-small cell lung cancer (NSCLC) survival outcomes. This study further validated …
improve non-small cell lung cancer (NSCLC) survival outcomes. This study further validated …
[HTML][HTML] Blood immune cell biomarkers in lung cancer patients undergoing treatment with a combination of chemotherapy and immune checkpoint blockade
M Möller, S Turzer, G Ganchev, A Wienke, W Schütte… - Cancers, 2022 - mdpi.com
Simple Summary Tumor cells can evade destruction via immune cells by expressing
coinhibitory membrane molecules, which can suppress tumor-specific T cells. Immune …
coinhibitory membrane molecules, which can suppress tumor-specific T cells. Immune …
[HTML][HTML] Microrna, mrna, and proteomics biomarkers and therapeutic targets for improving lung cancer treatment outcomes
Simple Summary This study identified a set of 73 microRNAs (miRNAs) that can accurately
detect lung cancer tumors from normal lung tissues. Based on the consistent expression …
detect lung cancer tumors from normal lung tissues. Based on the consistent expression …
[HTML][HTML] A multi-omics network of a seven-gene prognostic signature for non-small cell lung cancer
There is an unmet clinical need to identify patients with early-stage non-small cell lung
cancer (NSCLC) who are likely to develop recurrence and to predict their therapeutic …
cancer (NSCLC) who are likely to develop recurrence and to predict their therapeutic …
[HTML][HTML] Single B cell gene co-expression networks implicated in prognosis, proliferation, and therapeutic responses in non-small cell lung cancer bulk tumors
Simple Summary This study presents novel insights on dysregulated B cell proliferation
networks in non-small cell lung cancer (NSCLC). Within this network, a nine-gene signature …
networks in non-small cell lung cancer (NSCLC). Within this network, a nine-gene signature …
[HTML][HTML] Inferencing Bulk Tumor and Single-Cell Multi-Omics Regulatory Networks for Discovery of Biomarkers and Therapeutic Targets
There are insufficient accurate biomarkers and effective therapeutic targets in current cancer
treatment. Multi-omics regulatory networks in patient bulk tumors and single cells can shed …
treatment. Multi-omics regulatory networks in patient bulk tumors and single cells can shed …
[HTML][HTML] Hub genes in non-small cell lung cancer regulatory networks
There are currently no accurate biomarkers for optimal treatment selection in early-stage
non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve …
non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve …
[HTML][HTML] Expression-Based Diagnosis, Treatment Selection, and Drug Development for Breast Cancer
Q Ye, J Wang, B Ducatman, RA Raese… - International Journal of …, 2023 - mdpi.com
There is currently no gene expression assay that can assess if premalignant lesions will
develop into invasive breast cancer. This study sought to identify biomarkers for selecting …
develop into invasive breast cancer. This study sought to identify biomarkers for selecting …