Abstract The use of Next Generation Sequencing (NGS) to interrogate cell-free DNA (cfDNA)
as a transplant diagnostic provides a crucial step in improving the accuracy of post …

Background: Acute cellular rejection is a major determinant of mortality and
retransplantation after heart transplantation. We sought to evaluate the prognostic …

We discuss the early history of the structure of DNA and its involvement in gene structure as
well as its mobility in and between cells and between tissues in the form of circulating cell …

BACKGROUND Heart transplantation provides a significant improvement in survival and
quality of life for patients with end-stage heart disease, however many recipients experience …

Background Acute cellular rejection (ACR) is a major barrier to the long-term survival of
cardiac allografts. Although immune cells are well known to play critical roles in ACR, the …

There is a critical need for biomarkers of acute cellular rejection (ACR) in organ
transplantation. We hypothesized that ACR leads to changes in donor-reactive T cell small …

Purpose This study aimed to identify and correlate pathological findings with clinical
outcomes in patients after orthotopic heart transplantation (OHT) who either died or …

Scarcity of high-quality organs, suboptimal organ quality assessment, unsatisfactory pre-
implantation procedures, and poor long-term organ and patient survival are the main …

Background Myocardial strain imaging by speckle tracking echocardiography has
demonstrated significant prognostic utility in several diseases. However, the association of …

Several artificial intelligence (AI) and machine learning (ML) algorithms have been
constructed for cardiovascular medicine applications. These models have the potential to …