Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

The Arp2/3 complex is an evolutionary conserved molecular machine that generates
branched actin networks. When activated, the Arp2/3 complex contributes the actin …

We reconstructed the structure of actin filament branch junctions formed by fission yeast
Arp2/3 complex at 3.5 Å resolution from images collected by electron cryo-microscopy …

Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive
cellular processes such as lamellipodial protrusion and endocytosis. Arp2/3 complex is …

Arp2/3 complex generates branched actin networks that drive fundamental processes such
as cell motility and cytokinesis. The complex comprises seven proteins, including actin …

The actin-related protein (Arp) 2/3 complex nucleates branched actin filament networks
pivotal for cell migration, endocytosis and pathogen infection. Its activation is tightly …

Cortactin coactivates Arp2/3 complex synergistically with WASP-family nucleation-promoting
factors (NPFs) and stabilizes branched networks by linking Arp2/3 complex to F-actin. It is …

Branched actin filaments are found in many key cellular structures. Branches are nucleated
by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to …

Abstract Arp2/3 complex, a crucial actin filament nucleator, undergoes structural
rearrangements during activation by nucleation-promoting factors (NPFs). However, the …

Actin-related protein (Arp) 2/3 complex nucleates branched actin networks that drive cell
motility. It consists of seven proteins, including two actin-related subunits (Arp2 and Arp3) …