Virus-like particles: fundamentals and biomedical applications
JL Mejía-Méndez, R Vazquez-Duhalt… - International journal of …, 2022 - mdpi.com
Nanotechnology is a fast-evolving field focused on fabricating nanoscale objects for
industrial, cosmetic, and therapeutic applications. Virus-like particles (VLPs) are self …
industrial, cosmetic, and therapeutic applications. Virus-like particles (VLPs) are self …
EBV-associated diseases: Current therapeutics and emerging technologies
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …
Four ounces can move a thousand pounds: the enormous value of nanomaterials in tumor immunotherapy
Z Chen, Z Yue, K Yang, C Shen… - Advanced …, 2023 - Wiley Online Library
The application of nanomaterials in healthcare has emerged as a promising strategy due to
their unique structural diversity, surface properties, and compositional diversity. In particular …
their unique structural diversity, surface properties, and compositional diversity. In particular …
[HTML][HTML] Integrating immunopeptidome analysis for the design and development of cancer vaccines
The repertoire of naturally presented peptides within the MHC (major histocompatibility
complex) or HLA (human leukocyte antigens) system on the cellular surface of every …
complex) or HLA (human leukocyte antigens) system on the cellular surface of every …
[HTML][HTML] Nanocarrier vaccine therapeutics for global infectious and chronic diseases
Immunization has the potential to become a viable weapon for the upcoming pandemic and
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …
Yeast-based virus-like particles as an emerging platform for vaccine development and delivery
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
Biomimetic nanoparticles for DC vaccination: a versatile approach to boost cancer immunotherapy
L Meng, Z Teng, S Yang, N Wang, YH Guan, X Chen… - Nanoscale, 2023 - pubs.rsc.org
Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …
Virus-based biological systems as next-generation carriers for the therapy of central nervous system diseases
I Nowak, M Madej, J Secemska, R Sarna… - Pharmaceutics, 2023 - mdpi.com
Central nervous system (CNS) diseases are currently a major challenge in medicine. One
reason is the presence of the blood–brain barrier, which is a significant limitation for …
reason is the presence of the blood–brain barrier, which is a significant limitation for …
Mechanisms of immune modulation in the tumor microenvironment and implications for targeted therapy
P Czajka-Francuz, MJ Prendes, A Mankan… - Frontiers in …, 2023 - frontiersin.org
The efficacy of cancer therapies is limited to a great extent by immunosuppressive
mechanisms within the tumor microenvironment (TME). Numerous immune escape …
mechanisms within the tumor microenvironment (TME). Numerous immune escape …
[HTML][HTML] Viral protein-based nanoparticles (part 2): Pharmaceutical applications
R Mellid-Carballal, S Gutierrez-Gutierrez… - European Journal of …, 2023 - Elsevier
ABSTRACT Viral protein nanoparticles (ViP NPs) such as virus-like particles and virosomes
are structures halfway between viruses and synthetic nanoparticles. The biological nature of …
are structures halfway between viruses and synthetic nanoparticles. The biological nature of …