As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

Ferroptosis, a novel form of regulated cell death, is characterized by imbalance of
intracellular iron and redox systems, resulting from overgeneration of toxic lipid peroxidation …

Manganese (Mn), as a cofactor of multiple enzymes, exhibits great significance to the human
body, plants and animals. It is also a critical raw material and alloying element. However …

Manganese (Mn) is an essential trace element required for various biological processes.
However, excess Mn causes serious side effects in humans, including parkinsonism. Thus …

Metal ion homeostasis is fundamental for life. Specifically, transition metals iron, manganese
and zinc play a pivotal role in mitochondrial metabolism and energy generation, anti …

Aims: Excessive manganese (Mn) exposure is toxic, and induces lipid deposition, but the
underlying mechanisms remain elusive. Herein, we explored how dietary Mn …

This review explains the origin of the LIV-1 family of zinc transporters, paying attention to
how this family of nine human proteins was originally discovered. Structural and functional …

Manganese (Mn) is a trace nutrient necessary for life but becomes neurotoxic at high
concentrations in the brain. The brain is a “privileged” organ that is separated from systemic …

Iron is essential for erythropoiesis and other biological processes, but is toxic in excess.
Dietary absorption of iron is a highly regulated process and is a major determinant of body …

Manganese (Mn), a cofactor for various enzyme classes, is an essential trace metal for all
organisms. However, overexposure to Mn causes neurotoxicity. Here, we evaluated the …