T-cell epitope vaccine design by immunoinformatics
A Patronov, I Doytchinova - Open biology, 2013 - royalsocietypublishing.org
Vaccination is generally considered to be the most effective method of preventing infectious
diseases. All vaccinations work by presenting a foreign antigen to the immune system in …
diseases. All vaccinations work by presenting a foreign antigen to the immune system in …
Design of a multiepitope‐based peptide vaccine against the e protein of human COVID‐19: an immunoinformatics approach
MI Abdelmageed, AH Abdelmoneim… - BioMed research …, 2020 - Wiley Online Library
Background. A new endemic disease has spread across Wuhan City, China, in December
2019. Within few weeks, the World Health Organization (WHO) announced a novel …
2019. Within few weeks, the World Health Organization (WHO) announced a novel …
[HTML][HTML] The immunoinhibitory B7-H1 molecule as a potential target in cancer: killing many birds with one stone
S Afreen, S Dermime - Hematology/oncology and stem cell therapy, 2014 - Elsevier
Over expression of B7-H1 (also named PDL-1 or CD 274) molecule in cancer has been
linked to worse prognosis and resistance to anti-cancer therapies in several malignancies …
linked to worse prognosis and resistance to anti-cancer therapies in several malignancies …
Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer
Recent studies in multiple epithelial cancers have shown that the inhibitory receptor
programmed cell death 1 (PD-1) is expressed on tumor-infiltrating lymphocytes and/or …
programmed cell death 1 (PD-1) is expressed on tumor-infiltrating lymphocytes and/or …
The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk …
H Ghebeh, S Mohammed, A Al-Omair, A Qattant… - Neoplasia, 2006 - Elsevier
B7-H1 molecule increases the apoptosis of tumorreactive T lymphocytes and reduces their
immunogenicity. Breast cancer is the second most common cause of mortality after lung …
immunogenicity. Breast cancer is the second most common cause of mortality after lung …
[HTML][HTML] Novel multi epitope-based vaccine against monkeypox virus: vaccinomic approach
While mankind is still dealing with the COVID-19 pandemic, a case of monkeypox virus
(MPXV) has been reported to the WHO on May 7, 2022. Monkeypox is a viral zoonotic …
(MPXV) has been reported to the WHO on May 7, 2022. Monkeypox is a viral zoonotic …
[HTML][HTML] Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic …
H Ghebeh, C Lehe, E Barhoush, K Al-Romaih… - Breast Cancer …, 2010 - Springer
Abstract Introduction B7-H1 (PD-L1, CD274) is a T cell inhibitory molecule expressed in
many types of cancer, leading to immune escape of tumor cells. Indeed, in previous reports …
many types of cancer, leading to immune escape of tumor cells. Indeed, in previous reports …
CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL …
MS Bijker, SJF van den Eeden, KL Franken… - The Journal of …, 2007 - journals.aai.org
Therapeutic vaccination trials, in which patients with cancer were vaccinated with minimal
CTL peptide in oil-in-water formulations, have met with limited success. Many of these …
CTL peptide in oil-in-water formulations, have met with limited success. Many of these …
[HTML][HTML] Multi-epitope vaccine for monkeypox using pan-genome and reverse vaccinology approaches
Outbreaks of monkeypox virus infections have imposed major health concerns worldwide,
with high morbidity threats to children and immunocompromised adults. Although …
with high morbidity threats to children and immunocompromised adults. Although …
Nanostructured thin films via self‐assembly of block copolymers
G Krausch, R Magerle - Advanced Materials, 2002 - Wiley Online Library
Thin films of incompatible block copolymers self‐assemble into highly regular
supramolecular structures with characteristic dimensions in the 10–100 nm regime. There is …
supramolecular structures with characteristic dimensions in the 10–100 nm regime. There is …