Current advances in RNA therapeutics for human diseases

H Zogg, R Singh, S Ro - International journal of molecular sciences, 2022 - mdpi.com
Following the discovery of nucleic acids by Friedrich Miescher in 1868, DNA and RNA were
recognized as the genetic code containing the necessary information for proper cell …

Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

From oxiranes to oligomers: Architectures of US FDA approved pharmaceuticals containing oxygen heterocycles

MD Delost, DT Smith, BJ Anderson… - Journal of Medicinal …, 2018 - ACS Publications
Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

Final results from a defibrotide treatment‐IND study for patients with hepatic veno‐occlusive disease/sinusoidal obstruction syndrome

NA Kernan, S Grupp, AR Smith, S Arai… - British journal of …, 2018 - Wiley Online Library
Hepatic veno‐occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially
life‐threatening complication of haematopoietic stem cell transplant (HSCT) conditioning …

Kidney injury and disease in patients with haematological malignancies

F Bridoux, P Cockwell, I Glezerman… - Nature Reviews …, 2021 - nature.com
Acute kidney injury (AKI) is common in patients with cancer, especially in those with
haematological malignancies. Kidney injury might be a direct consequence of the …

The use of defibrotide in blood and marrow transplantation

PG Richardson, E Carreras, M Iacobelli… - Blood …, 2018 - ashpublications.org
Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially
life-threatening complication of conditioning during hematopoietic stem cell transplantation …

Defibrotide: real-world management of veno-occlusive disease/sinusoidal obstructive syndrome after stem cell transplant

M Nauffal, HT Kim, PG Richardson, RJ Soiffer… - Blood …, 2022 - ashpublications.org
Hepatic veno-occlusive disease or sinusoidal obstructive syndrome (VOD/SOS) is a life-
threatening complication of hematopoietic stem cell transplantation (HSCT). Defibrotide is …

Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study

Y Wang, D Qiao, Y Li, F Xu - BMC gastroenterology, 2018 - Springer
Background Hepatic veno-occlusive disease (HVOD) caused by Gynura segetum has been
increasingly reported in China in recent years. The aim of this retrospective study was to …

New ultrasound techniques challenge the diagnosis of sinusoidal obstruction syndrome

CF Dietrich, C Trenker, T Fontanilla, C Görg… - Ultrasound in Medicine …, 2018 - Elsevier
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a
potentially life-threatening complication that can develop after hematopoietic cell …

[HTML][HTML] Consolidation therapy for newly diagnosed pediatric patients with high-risk neuroblastoma using Busulfan/Melphalan, autologous hematopoietic cell …

AC Talleur, BM Triplett, S Federico, E Mamcarz… - Biology of Blood and …, 2017 - Elsevier
The treatment of pediatric high-risk neuroblastoma is intensive and multimodal. Despite the
introduction of immunotherapy for minimal residual disease, survival rates remain …