Tolerance and resistance of microbial biofilms
Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …
Mechanisms and clinical importance of bacteriophage resistance
JE Egido, AR Costa… - FEMS microbiology …, 2022 - academic.oup.com
We are in the midst of a golden age of uncovering defense systems against bacteriophages.
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Current challenges and future opportunities of phage therapy
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …
global health might be devastating if novel antibacterial strategies are not quickly …
Understanding the impacts of bacteriophage viruses: from laboratory evolution to natural ecosystems
B Koskella, CA Hernandez… - Annual Review of …, 2022 - annualreviews.org
Viruses of bacteria (bacteriophages or phage) have broad effects on bacterial ecology and
evolution in nature that mediate microbial interactions, shape bacterial diversity, and …
evolution in nature that mediate microbial interactions, shape bacterial diversity, and …
[HTML][HTML] Translating phage therapy into the clinic: recent accomplishments but continuing challenges
A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
Drivers and consequences of bacteriophage host range
D Holtappels, P Alfenas-Zerbini… - FEMS Microbiology …, 2023 - academic.oup.com
Bacteriophages are obligate parasites of bacteria characterized by the breadth of hosts that
they can infect. This “host range” depends on the genotypes and morphologies of the phage …
they can infect. This “host range” depends on the genotypes and morphologies of the phage …
Biological foundations of successful bacteriophage therapy
C Venturini, A Petrovic Fabijan… - EMBO Molecular …, 2022 - embopress.org
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …
in nature, phages can be used to treat bacterial infections (phage therapy), including …
Eradicating biofilm infections: an update on current and prospective approaches
Highlights•Biofilm infections are heterogenous, persistent and recalcitrant.•The rise of
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …
Understanding the complex phage-host interactions in biofilm communities
Bacteriophages and bacterial biofilms are widely present in natural environments, a fact that
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
Bacteriophage–a promising alternative measure for bacterial biofilm control
F Tian, J Li, A Nazir, Y Tong - Infection and Drug Resistance, 2021 - Taylor & Francis
Bacterial biofilms can enhance bacteria's viability by providing resistance against antibiotics
and conventional disinfectants. The existence of biofilm is a serious threat to human health …
and conventional disinfectants. The existence of biofilm is a serious threat to human health …