The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory response. In the first part of this …

The immunology of porcine reproductive and respiratory syndrome virus (PRRS) begins with
an initial encounter of PRRSV with the pig. Regardless of the route of entry of PRRSV—via …

Background & Aims: The extent and severity of mucosal injury in inflammatory bowel
diseases are determined by the disequilibrium between 2 opposing processes: reparative …

Acute pancreatitis is an inflammatory disease of the pancreas which, in its most severe form,
is associated with multi-organ failure and death. Recently, signalling molecules and …

Approximately 20% of patients with acute pancreatitis develop a severe disease associated
with complications and high risk of mortality. The purpose of this study is to review …

The use of plant extracts to alleviate inflammatory diseases is centuries old and continues to
this day. This review assesses the current understanding of the use of such plants and …

Background & Aims: Activation of NF-κB/Rel has been implicated in the pathogenesis of
inflammatory bowel disease (IBD). Various drugs used in the treatment of IBD, such as …

There is increasing evidence that food‐derived polyphenols have a beneficial effect for
cancers. Our purpose was to determine the effect and mechanism of action of these …

Background Muscle wasting or sarcopenia arising from chronic inflammation is found in
60% of patients with Crohn's disease. Transcriptional protein NF‐κB reduces muscle …

BACKGROUND & AIMS:: Ethanol metabolism by pancreatic acinar cells and the role of its
metabolites in ethanol toxicity to the pancreas remain largely unknown. Here, we …