The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

Noninvasive Respiratory Support in Acute Respiratory Failure Noninvasive respiratory
support can be useful for cardiogenic pulmonary edema and COPD exacerbations. For other …

Importance High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic
respiratory failure and is widely applied in patients with COVID-19. Objective To assess …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is associated
with poor clinical outcomes. Although the importance and impact of lung-protective …

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Rationale: The role of inspiratory effort still has to be determined as a potential predictor of
noninvasive mechanical ventilation (NIV) failure in acute hypoxic de novo respiratory failure …

Neural respiratory drive, ie, the activity of respiratory centres controlling breathing, is an
overlooked physiologic variable which affects the pathophysiology and the clinical outcome …

The role of spontaneous breathing among patients with acute hypoxemic respiratory failure
and ARDS is debated: while avoidance of intubation with noninvasive ventilation (NIV) or …

Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

Rationale: High-flow nasal cannula (HFNC) and helmet noninvasive ventilation (NIV) are
used for the management of acute hypoxemic respiratory failure. Objectives: Physiological …